MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1788 · 46 genes shown · anchor PPE26 · open gene page → · ← back to 1 hop

Evidence: Min score 0
PE18 (family_assigned) — PE family protein PE18 PE18 PPE26 (family_assigned) — PPE family protein PPE26 PPE26 PPE25 (family_assigned) — PPE family protein PPE25 PPE25 PPE27 (family_assigned) — PPE family protein PPE27 PPE27 Rv3435c (family_assigned) — DUF4436 domain-containing protein Rv3435c Rv0245 (family_assigned) — flavin reductase family protein Rv0245 Rv0213c (requalified) — methyltransferase Rv0213c Rv2529 (family_assigned) — hypothetical protein Rv2529 Rv3434c (family_assigned) — rhomboid-like protein Rv3434c efp (requalified) — elongation factor P efp Rv1829 (family_assigned) — hypothetical protein Rv1829 adhA (family_assigned) — zinc-binding alcohol dehydrogenase family protein adhA rdgB (family_assigned) — RdgB/HAM1 family non-canonical purine NTP pyrophos rdgB Rv1352 (family_assigned) — hypothetical protein Rv1352 Rv3095 (family_assigned) — helix-turn-helix domain-containing protein Rv3095 Rv1786 (requalified) — ferredoxin Rv1786 Rv1794 (family_assigned) — ESX secretion-associated protein EspG Rv1794 PE25 (family_assigned) — PE family protein PE25 PE25 PE19 (family_assigned) — PE family protein PE19 PE19 esxN (requalified) — ESAT-6 like protein EsxN esxN Rv3575c (family_assigned) — LacI family DNA-binding transcriptional regulator Rv3575c Rv3433c (requalified) — NAD(P)H-hydrate dehydratase Rv3433c Rv2423 (requalified) — class I SAM-dependent methyltransferase Rv2423 Rv3166c (family_assigned) — DUF4129 domain-containing protein Rv3166c Rv3843c (family_assigned) — DUF4328 domain-containing protein Rv3843c Rv2067c (requalified) — class I SAM-dependent methyltransferase Rv2067c Rv3007c (family_assigned) — flavin reductase family protein Rv3007c fadE5 (requalified) — acyl-CoA dehydrogenase fadE5 Rv0246 (family_assigned) — integral membrane protein Rv0246 Rv3192 (family_assigned) — hypothetical protein Rv3192 fgd1 (requalified) — glucose-6-phosphate dehydrogenase (coenzyme-F420) fgd1 Rv3833 (family_assigned) — helix-turn-helix transcriptional regulator Rv3833 nadR (requalified) — nicotinamide-nucleotide adenylyltransferase nadR ppk2 (requalified) — polyphosphate kinase ppk2 fadD4 (requalified) — fatty-acid--CoA ligase FadD4 fadD4 hemN (requalified) — oxygen-independent coproporphyrinogen III oxidase hemN Rv3729 (requalified) — transferase Rv3729 Rv2954c (requalified) — [2%2C4-di-O-methyl-alpha-L-fucopyranosyl-(1->3)-al Rv2954c topA (requalified) — type I DNA topoisomerase topA polA (requalified) — DNA polymerase I polA lprE (family_assigned) — LppP/LprE family lipoprotein lprE Rv2090 (requalified) — 5'-3' exonuclease Rv2090 rplA (requalified) — 50S ribosomal protein L1 rplA recA (requalified) — intein-containing recombinase RecA recA gadB (requalified) — glutamate decarboxylase gadB glmS (requalified) — glutamine--fructose-6-phosphate transaminase (isom glmS

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.