MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1750c · 43 genes shown · anchor fadD18 · open gene page → · ← back to 1 hop

Evidence: Min score 0
fadD1 (requalified) — fatty-acid--CoA ligase FadD1 fadD1 fadD18 (requalified) — fatty-acid--CoA ligase FadD18 fadD18 fadD19 (requalified) — acyl-CoA synthetase fadD19 rplF (requalified) — 50S ribosomal protein L6 rplF pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks12 (requalified) — type I polyketide synthase pks12 mas (requalified) — mycocerosate synthase mas pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks13 (requalified) — polyketide synthase Pks13 pks13 mbtE (requalified) — peptide synthetase mbtE pks1 (requalified) — polyketide synthase pks1 ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB fadD22 (requalified) — p-hydroxybenzoic acid--AMP ligase FadD22 fadD22 fadD10 (requalified) — fatty-acid--CoA ligase FadD10 fadD10 fadD17 (requalified) — long-chain-fatty-acid--CoA ligase FadD17 fadD17 fadE26 (requalified) — acyl-CoA dehydrogenase fadE26 cyp125 (requalified) — steroid C26-monooxygenase cyp125 echA19 (family_assigned) — crotonase/enoyl-CoA hydratase family protein echA19 ltp4 (family_assigned) — thiolase domain-containing protein ltp4 Rv3521 (family_assigned) — hypothetical protein Rv3521 rpsD (requalified) — 30S ribosomal protein S4 rpsD rplW (requalified) — 50S ribosomal protein L23 rplW rpsG (requalified) — 30S ribosomal protein S7 rpsG rplS (requalified) — 50S ribosomal protein L19 rplS rpsR1 (requalified) — 30S ribosomal protein S18 rpsR1 rplB (requalified) — 50S ribosomal protein L2 rplB fas (requalified) — fatty acid synthase fas fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD mbtB (requalified) — phenyloxazoline synthase MbtB mbtB ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD papA1 (requalified) — acyltransferase PapA1 papA1 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 mbtC (requalified) — polyketide synthetase MbtC mbtC mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG pks15 (requalified) — polyketide synthase pks15 ppsA (requalified) — phthiocerol type I polyketide synthase PpsA ppsA fadD26 (requalified) — long-chain-fatty-acid--AMP ligase FAAL26/FadD26 fadD26

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.