MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1663 · 46 genes shown · anchor pks8 · open gene page → · ← back to 1 hop

Evidence: Min score 0
pks17 (requalified) — polyketide synthase pks17 pks8 (requalified) — polyketide synthase pks8 fas (requalified) — fatty acid synthase fas pks9 (requalified) — type I polyketide synthase pks9 pks15 (requalified) — polyketide synthase pks15 mbtC (requalified) — polyketide synthetase MbtC mbtC pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 nuoC (family_assigned) — NADH-quinone oxidoreductase subunit C nuoC nuoI (family_assigned) — NADH-quinone oxidoreductase subunit NuoI nuoI nuoB (family_assigned) — NADH-quinone oxidoreductase subunit B nuoB pks7 (requalified) — type I polyketide synthase pks7 pks13 (requalified) — polyketide synthase Pks13 pks13 fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD mbtB (requalified) — phenyloxazoline synthase MbtB mbtB pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mas (requalified) — mycocerosate synthase mas accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 pks6 (requalified) — membrane bound polyketide synthase pks6 fadB5 (family_assigned) — medium chain dehydrogenase/reductase family protei fadB5 Rv3777 (requalified) — oxidoreductase Rv3777 mbtE (requalified) — peptide synthetase mbtE pks1 (requalified) — polyketide synthase pks1 fadD29 (requalified) — long-chain-fatty-acid--AMP ligase FadD29 fadD29 fadD22 (requalified) — p-hydroxybenzoic acid--AMP ligase FadD22 fadD22 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD mbtF (requalified) — peptide synthetase mbtF papA3 (requalified) — acyltransferase PapA3 papA3 fadB4 (family_assigned) — NADPH:quinone oxidoreductase family protein fadB4 nuoF (family_assigned) — NADH-quinone oxidoreductase subunit NuoF nuoF nuoD (family_assigned) — NADH dehydrogenase (quinone) subunit D nuoD nuoA (family_assigned) — NADH-quinone oxidoreductase subunit A nuoA nuoM (family_assigned) — NADH-quinone oxidoreductase subunit M nuoM nuoE (family_assigned) — NADH-quinone oxidoreductase subunit NuoE nuoE nuoN (family_assigned) — NADH-quinone oxidoreductase subunit NuoN nuoN nuoJ (family_assigned) — NADH-quinone oxidoreductase subunit J nuoJ nuoG (family_assigned) — NADH-quinone oxidoreductase subunit G nuoG nuoH (family_assigned) — NADH-quinone oxidoreductase subunit NuoH nuoH nuoK (family_assigned) — NADH-quinone oxidoreductase subunit NuoK nuoK mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 kasA (requalified) — 3-oxoacyl-ACP synthase KasA kasA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.