MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1662 · 31 genes shown · anchor pks17 · open gene page → · ← back to 1 hop

Evidence: Min score 0
pks8 (requalified) — polyketide synthase pks8 pks17 (requalified) — polyketide synthase pks17 pks7 (requalified) — type I polyketide synthase pks7 pks9 (requalified) — type I polyketide synthase pks9 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC mas (requalified) — mycocerosate synthase mas pks12 (requalified) — type I polyketide synthase pks12 nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp tesA (requalified) — thioesterase TesA tesA mbtE (requalified) — peptide synthetase mbtE fas (requalified) — fatty acid synthase fas pks15 (requalified) — polyketide synthase pks15 mbtC (requalified) — polyketide synthetase MbtC mbtC pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD fadB5 (family_assigned) — medium chain dehydrogenase/reductase family protei fadB5 Rv3777 (requalified) — oxidoreductase Rv3777 mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH papA1 (requalified) — acyltransferase PapA1 papA1 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB fadD10 (requalified) — fatty-acid--CoA ligase FadD10 fadD10 ppsA (requalified) — phthiocerol type I polyketide synthase PpsA ppsA mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.