MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1639c · 46 genes shown · anchor lysX · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1639c (family_assigned) — alpha/beta hydrolase family protein Rv1639c Rv1638A (family_assigned) — hypothetical protein Rv1638A mftF (requalified) — mycofactocin biosynthesis glycosyltransferase MftF mftF Rv2160A (family_assigned) — Conserved hypothetical protein Rv2160A mftE (requalified) — mycofactocin biosynthesis peptidyl-dipeptidase Mft mftE lysX (requalified) — bifunctional lysine--tRNA ligase/phosphatidylglyce lysX Rv3479 (requalified) — transmembrane protein Rv3479 glnX (requalified) — protein kinase G-activating protein GlnX glnX adhD (requalified) — NDMA-dependent alcohol dehydrogenase adhD mscR (requalified) — S-(hydroxymethyl)mycothiol dehydrogenase mscR adhB (requalified) — alcohol dehydrogenase B adhB adhE1 (family_assigned) — zinc-type alcohol dehydrogenase subunit E adhE1 lppW (family_assigned) — hypothetical protein lppW Rv2468c (requalified) — hypothetical protein Rv2468c Rv3205c (family_assigned) — hypothetical protein Rv3205c Rv2474c (family_assigned) — hypothetical protein Rv2474c Rv1083 (dark) — hypothetical protein Rv1083 cei (requalified) — envelope integrity protein Cei cei mftG (family_assigned) — mycofactocin system GMC family oxidoreductase MftG mftG mftC (requalified) — mycofactocin radical SAM maturase mftC mftB (requalified) — mycofactocin biosynthesis chaperone MftB mftB mftD (requalified) — pre-mycofactocin synthase MftD mftD mftR (family_assigned) — mycofactocin system transcriptional regulator mftR Rv2160c (family_assigned) — Conserved hypothetical protein Rv2160c Rv2159c (family_assigned) — carboxymuconolactone decarboxylase family protein Rv2159c Rv2161c (family_assigned) — TIGR03619 family F420-dependent LLM class oxidored Rv2161c murF (requalified) — UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanin murF murE (requalified) — UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-d murE murX (requalified) — phospho-N-acetylmuramoyl-pentapeptide-transferase murX lysS (requalified) — lysine--tRNA ligase lysS gltS (requalified) — glutamate--tRNA ligase gltS ileS (requalified) — isoleucine--tRNA ligase ileS metS (requalified) — methionine--tRNA ligase metS guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA argS (requalified) — arginine--tRNA ligase argS Rv1947 (family_assigned) — hypothetical protein Rv1947 vapB5 (family_assigned) — type II toxin-antitoxin system Phd/YefM family ant vapB5 Rv0470A (family_assigned) — hypothetical protein Rv0470A vapC4 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC4 vapC8 (family_assigned) — PIN domain-containing protein vapC8 pknG (requalified) — serine/threonine protein kinase PknG pknG glnH (family_assigned) — glutamate ABC transporter substrate-binding protei glnH fbpC (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpC fbpB (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpB mutT3 (requalified) — 8-oxo-dGTP diphosphatase mutT3 fbpA (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.