Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1607 · 38 genes shown · anchor vapC21 · open gene page → · ← back to 1 hop

Evidence: Min score 0
chaA (requalified) — calcium:proton antiporter chaA vapC21 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC21 hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF impA (family_assigned) — inositol monophosphatase family protein impA hisI (requalified) — phosphoribosyl-AMP cyclohydrolase hisI hisA (requalified) — bifunctional 1-(5-phosphoribosyl)-5-((5-phosphorib hisA hisH (family_assigned) — imidazole glycerol phosphate synthase subunit HisH hisH hisD (requalified) — histidinol dehydrogenase hisD ccsA (requalified) — c-type cytochrome biogenesis protein CcsB ccsA hisB (requalified) — imidazoleglycerol-phosphate dehydratase HisB hisB hisC1 (requalified) — histidinol-phosphate aminotransferase hisC1 yhjD (requalified) — inner membrane protein YhjD yhjD Rv2707 (family_assigned) — YihY/virulence factor BrkB family protein Rv2707 vapB21 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB21 hsdM (requalified) — class I SAM-dependent DNA methyltransferase hsdM vapC42 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC42 vapB42 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB42 hsdS (family_assigned) — restriction endonuclease subunit S hsdS Rv2762c (family_assigned) — winged helix-turn-helix domain-containing protein Rv2762c suhB (requalified) — inositol-1-monophosphatase SuhB suhB hisE (requalified) — phosphoribosyl-ATP pyrophosphatase hisE Rv0528 (requalified) — cytochrome c biogenesis protein ResB Rv0528 Rv0526 (requalified) — thioredoxin Rv0526 ccdA (requalified) — cytochrome C-type biogenesis protein CcdA ccdA hemL (requalified) — glutamate-1-semialdehyde 2%2C1-aminomutase hemL Rv0525 (family_assigned) — histidine phosphatase family protein Rv0525 hemD (requalified) — uroporphyrin-III C-methyltransferase hemD trpS (requalified) — tryptophan--tRNA ligase trpS Rv3013 (family_assigned) — amino acid-binding protein Rv3013 Rv3337 (family_assigned) — Conserved hypothetical protein Rv3337 Rv3338 (family_assigned) — Conserved hypothetical protein Rv3338 Rv3753c (family_assigned) — hypothetical protein Rv3753c Rv2446c (dark) — DUF4233 domain-containing protein Rv2446c Rv2705c (family_assigned) — DUF952 domain-containing protein Rv2705c Rv2706c (dark) — hypothetical protein Rv2706c Rv0876c (requalified) — MFS transporter Rv0876c rseA (requalified) — anti-sigma E factor RseA rseA Rv2323c (family_assigned) — hypothetical protein Rv2323c

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.