MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1594 · 46 genes shown · anchor nadB · open gene page → · ← back to 1 hop

Evidence: Min score 0
nadA (requalified) — quinolinate synthetase A nadA nadB (requalified) — L-aspartate oxidase nadB nadC (requalified) — carboxylating nicotinate-nucleotide diphosphorylas nadC Rv1593c (family_assigned) — NUDIX domain-containing protein Rv1593c cysE (requalified) — serine O-acetyltransferase cysE gmk (requalified) — guanylate kinase gmk valS (requalified) — valine--tRNA ligase valS Rv1597 (family_assigned) — methyltransferase domain-containing protein Rv1597 gltB (family_assigned) — glutamate synthase large subunit gltB iscS (family_assigned) — cysteine desulfurase family protein iscS bioB (requalified) — biotin synthase BioB bioB Rv1592c (family_assigned) — lipase family protein Rv1592c bioD (requalified) — dethiobiotin synthase bioD ansA (requalified) — asparaginase ansA pyrB (family_assigned) — aspartate carbamoyltransferase catalytic subunit pyrB purA (requalified) — adenylosuccinate synthase purA argG (requalified) — argininosuccinate synthase argG pncB1 (requalified) — nicotinate phosphoribosyltransferase pncB1 pncB2 (requalified) — nicotinate phosphoribosyltransferase pncB2 cinA (requalified) — competence/damage-inducible protein A cinA nadD (requalified) — nicotinate-nucleotide adenylyltransferase nadD Rv0081 (family_assigned) — lsr2/espR transcriptional regulator Rv0081 cysK1 (requalified) — O-acetylserine sulfhydrylase cysK1 Rv3684 (requalified) — lyase Rv3684 cbs (requalified) — cystathionine beta-synthase cbs sdaA (requalified) — L-serine ammonia-lyase sdaA cysS1 (requalified) — cysteine--tRNA ligase cysS1 serB2 (requalified) — phosphoserine phosphatase SerB serB2 rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA apt (requalified) — adenine phosphoribosyltransferase apt pykA (requalified) — pyruvate kinase pykA ndkA (requalified) — nucleoside-diphosphate kinase ndkA hpt (requalified) — hypoxanthine phosphoribosyltransferase hpt folC (requalified) — bifunctional tetrahydrofolate synthase/dihydrofola folC Rv2446c (dark) — DUF4233 domain-containing protein Rv2446c ileS (requalified) — isoleucine--tRNA ligase ileS leuS (requalified) — leucine--tRNA ligase leuS Rv2970A (family_assigned) — hypothetical protein Rv2970A gltD (family_assigned) — glutamate synthase subunit beta gltD fprA (requalified) — ferredoxin--NADP(+) reductase FprA fprA fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH fprB (requalified) — FAD-dependent oxidoreductase fprB carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB glnA1 (requalified) — type I glutamate--ammonia ligase glnA1 Rv1465 (family_assigned) — SUF system NifU family Fe-S cluster assembly prote Rv1465

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.