Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1561 · 46 genes shown · anchor vapB11 · open gene page → · ← back to 1 hop

Evidence: Min score 0
vapC11 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC11 vapB11 (requalified) — antitoxin VapB11 vapB11 vapB15 (requalified) — antitoxin VapB15 vapB15 Rv3677c (requalified) — MBL fold metallo-hydrolase Rv3677c Rv2531c (requalified) — amino acid decarboxylase Rv2531c ilvA (requalified) — threonine ammonia-lyase ilvA vapC30 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC30 Rv0158 (family_assigned) — TetR/AcrR family transcriptional regulator Rv0158 Rv1558 (requalified) — F420H(2)-dependent quinone reductase Rv1558 mmpL6 (requalified) — transmembrane transport protein MmpL6 mmpL6 vapC42 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC42 vapB2 (requalified) — type II toxin-antitoxin system antitoxin VapB2 vapB2 Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 vapC15 (family_assigned) — PIN domain nuclease vapC15 cobB (requalified) — NAD-dependent protein deacylase cobB Rv1395 (family_assigned) — HTH-type transcriptional regulator Rv1395 parD1 (family_assigned) — type II toxin-antitoxin system ParD family antitox parD1 Rv2008c (family_assigned) — hypothetical protein Rv2008c vapC2 (family_assigned) — PIN domain nuclease vapC2 vapC5 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC5 vapC4 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC4 Rv3678c (family_assigned) — RidA family protein Rv3678c Rv3678A (family_assigned) — hypothetical protein Rv3678A Rv3680 (family_assigned) — ArsA family ATPase Rv3680 Rv3679 (family_assigned) — ArsA family ATPase Rv3679 Rv3040c (requalified) — NUDIX hydrolase Rv3040c vapB39 (requalified) — antitoxin VapB39 vapB39 arcA (requalified) — arginine deiminase arcA argH (requalified) — argininosuccinate lyase argH Rv1722 (requalified) — biotin carboxylase Rv1722 vapC39 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC39 ilvN (family_assigned) — acetolactate synthase small subunit ilvN ilvB1 (family_assigned) — acetolactate synthase large subunit IlvB ilvB1 leuB (requalified) — 3-isopropylmalate dehydrogenase leuB thrC (requalified) — threonine synthase thrC ilvB2 (family_assigned) — thiamine pyrophosphate-binding protein ilvB2 ilvG (requalified) — acetolactate synthase ilvG vapB30 (requalified) — type II toxin-antitoxin system antitoxin VapB30 vapB30 vapB34 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB34 ethR (family_assigned) — HTH-type transcriptional regulator EthR ethR sirR (family_assigned) — manganese-binding transcriptional regulator MntR sirR kstR2 (family_assigned) — TetR family transcriptional regulator KstR2 kstR2 Rv3488 (family_assigned) — PadR family transcriptional regulator Rv3488 Rv3060c (family_assigned) — FCD domain-containing protein Rv3060c iniR (family_assigned) — isoniazid response ATPase/transcriptional regulato iniR Rv0044c (requalified) — LLM class F420-dependent oxidoreductase Rv0044c

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.