MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1492 · 46 genes shown · anchor mutB · open gene page → · ← back to 1 hop

Evidence: Min score 0
mutA (family_assigned) — methylmalonyl-CoA mutase small subunit mutA mutB (requalified) — methylmalonyl-CoA mutase mutB Rv1489A (family_assigned) — hypothetical protein Rv1489A meaB (requalified) — methylmalonyl Co-A mutase-associated GTPase MeaB meaB Rv1322A (family_assigned) — hypothetical protein Rv1322A sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC sucD (family_assigned) — succinyl-CoA ligase subunit alpha sucD bkdC (family_assigned) — dihydrolipoamide acetyltransferase family protein bkdC dlaT (requalified) — 2-oxoglutarate dehydrogenase%2C E2 component%2C di dlaT Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c citA (requalified) — citrate synthase 2 citA pca (requalified) — pyruvate carboxylase pca mqo (requalified) — malate dehydrogenase (quinone) mqo Rv1489 (family_assigned) — hypothetical protein Rv1489 Rv0513 (family_assigned) — DUF3093 domain-containing protein Rv0513 Rv3802c (requalified) — phospholipase Rv3802c mazE4 (requalified) — type II toxin-antitoxin system antitoxin MazE4 mazE4 mazF4 (requalified) — type II toxin-antitoxin system toxin endoribonucle mazF4 Rv1491c (family_assigned) — TVP38/TMEM64 family protein Rv1491c accD5 (family_assigned) — acyl-CoA carboxylase subunit beta accD5 accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 accA2 (family_assigned) — biotin carboxylase N-terminal domain-containing pr accA2 Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c sdhC (family_assigned) — succinate dehydrogenase%2C cytochrome b556 subunit sdhC sdhB (family_assigned) — succinate dehydrogenase iron-sulfur subunit sdhB sdhD (family_assigned) — succinate dehydrogenase hydrophobic membrane ancho sdhD Rv0247c (family_assigned) — succinate dehydrogenase/fumarate reductase iron-su Rv0247c sdhA (family_assigned) — succinate dehydrogenase flavoprotein subunit sdhA bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB bkdA (family_assigned) — pyruvate dehydrogenase (acetyl-transferring) E1 co bkdA lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC aceE (requalified) — pyruvate dehydrogenase E1 component aceE Rv0843 (family_assigned) — thiamine pyrophosphate-dependent dehydrogenase E1 Rv0843 accA1 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA1 Rv2454c (family_assigned) — 2-oxoacid:ferredoxin oxidoreductase subunit beta Rv2454c icd2 (requalified) — NADP-dependent isocitrate dehydrogenase icd2 aroF (requalified) — chorismate synthase aroF pta (requalified) — phosphate acetyltransferase pta acn (requalified) — iron-regulated aconitate hydratase Acn acn mdh (requalified) — malate dehydrogenase mdh acs (requalified) — acetate--CoA ligase acs gltA2 (requalified) — citrate synthase gltA2 glcB (requalified) — malate synthase G glcB prpC (requalified) — 2-methylcitrate synthase prpC pykA (requalified) — pyruvate kinase pykA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.