MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1474c · 46 genes shown · anchor acn · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1474c (family_assigned) — helix-turn-helix domain-containing protein Rv1474c acn (requalified) — iron-regulated aconitate hydratase Acn acn Rv0674 (family_assigned) — PaaX family transcriptional regulator C-terminal d Rv0674 35kd_ag (family_assigned) — hypothetical protein 35kd_ag Rv2179c (requalified) — polyadenylate-specific 3'-exoribonuclease AS Rv2179c Rv0948c (requalified) — chorismate mutase Rv0948c lprD (family_assigned) — hypothetical protein lprD Rv1638A (family_assigned) — hypothetical protein Rv1638A Rv1476 (family_assigned) — DUF6676 family protein Rv1476 Rv2446c (dark) — DUF4233 domain-containing protein Rv2446c Rv0863 (family_assigned) — hypothetical protein Rv0863 Rv2468c (requalified) — hypothetical protein Rv2468c Rv3205c (family_assigned) — hypothetical protein Rv3205c prpC (requalified) — 2-methylcitrate synthase prpC citA (requalified) — citrate synthase 2 citA gltA2 (requalified) — citrate synthase gltA2 icd1 (requalified) — NADP-dependent isocitrate dehydrogenase icd1 icd2 (requalified) — NADP-dependent isocitrate dehydrogenase icd2 icl1 (requalified) — isocitrate lyase icl1 echA4 (family_assigned) — crotonase/enoyl-CoA hydratase family protein echA4 echA5 (requalified) — enoyl-CoA hydratase EchA5 echA5 fadE8 (family_assigned) — acyl-CoA dehydrogenase family protein fadE8 Rv0273c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0273c moxR2 (family_assigned) — MoxR family ATPase moxR2 Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 clgR (family_assigned) — transcriptional regulator ClgR clgR Rv2743c (family_assigned) — hypothetical protein Rv2743c htpX (requalified) — zinc metalloprotease HtpX htpX sigB (family_assigned) — sigma-70 family RNA polymerase sigma factor SigB sigB Rv2180c (family_assigned) — integral membrane protein Rv2180c aroG (requalified) — 3-deoxy-7-phosphoheptulonate synthase class II aroG Rv2181 (requalified) — alpha-(1-2)-phosphatidylinositol mannoside mannosy Rv2181 aroF (requalified) — chorismate synthase aroF tyrA (requalified) — prephenate dehydrogenase TyrA tyrA pheA (requalified) — prephenate dehydratase pheA trpE (requalified) — anthranilate synthase component I trpE Rv1885c (requalified) — chorismate mutase Rv1885c Rv1342c (family_assigned) — hypothetical protein Rv1342c Rv3850 (family_assigned) — DUF6474 family protein Rv3850 Rv0049 (dark) — hypothetical protein Rv0049 Rv0358 (requalified) — peptidase M50 Rv0358 Rv1209 (family_assigned) — DivIVA domain-containing protein Rv1209 Rv1639c (family_assigned) — alpha/beta hydrolase family protein Rv1639c Rv2474c (family_assigned) — hypothetical protein Rv2474c Rv1083 (dark) — hypothetical protein Rv1083 cei (requalified) — envelope integrity protein Cei cei

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.