MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1443c · 46 genes shown · anchor lppF · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1443c (family_assigned) — hypothetical protein Rv1443c Rv3594 (requalified) — N-acetylmuramoyl-L-alanine amidase Rv3594 lppF (requalified) — haloacid dehalogenase-like hydrolase lppF Rv1754c (requalified) — DUF4185 domain-containing protein Rv1754c lprI (family_assigned) — MliC family protein lprI espK (family_assigned) — ESX-1 secretion-associated protein EspK espK eccE1 (family_assigned) — type VII secretion system ESX-1 subunit EccE1 eccE1 esxA (requalified) — ESAT-6 protein EsxA esxA Rv1978 (requalified) — class I SAM-dependent methyltransferase Rv1978 Rv1288 (requalified) — esterase Rv1288 Rv0097 (family_assigned) — TauD/TfdA family dioxygenase Rv0097 eccD1 (family_assigned) — type VII secretion system ESX-1 subunit EccD1 eccD1 Rv1230c (family_assigned) — lytic transglycosylase domain-containing protein Rv1230c hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF Rv2319c (requalified) — universal stress protein Rv2319c Rv3668c (requalified) — protease Rv3668c spmT (requalified) — sphingomyelinase spmT Rv0312 (family_assigned) — Hsp70 family protein Rv0312 Rv0431 (requalified) — tuberculin-like peptide Rv0431 rpsF (requalified) — 30S ribosomal protein S6 rpsF Rv3707c (requalified) — hypothetical protein Rv3707c frdD (family_assigned) — fumarate reductase subunit FrdD frdD glbN (requalified) — group 1 truncated hemoglobin GlbN glbN frdC (family_assigned) — fumarate reductase subunit C frdC vapC24 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC24 Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c Rv0613c (family_assigned) — SEC-C domain-containing protein Rv0613c espB (requalified) — type VII secretion system ESX-1 target EspB espB iniB (requalified) — isoniazid-induced protein IniB iniB PPE8 (family_assigned) — PPE family protein PPE8 PPE8 PPE56 (family_assigned) — PPE family protein PPE56 PPE56 mycP1 (requalified) — type VII secretion system ESX-1 serine protease my mycP1 eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 esxB (family_assigned) — type VII secretion system ESX-1 WXG100 family targ esxB esxO (requalified) — type VII secretion system effector EsxO esxO esxW (requalified) — type VII secretion system protein EsxW esxW Rv2687c (family_assigned) — fluoroquinolone transporter permease Rv2687c Rv2686c (family_assigned) — fluoroquinolones efflux ABC transporter permease Rv2686c rsmA (requalified) — anti-sigma-M factor RsmA rsmA Rv0210 (family_assigned) — hypothetical protein Rv0210 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 Rv3604c (dark) — DUF6779 domain-containing protein Rv3604c Rv1287 (family_assigned) — RrF2 family transcriptional regulator Rv1287 Rv1289 (family_assigned) — hypothetical protein Rv1289 fadD10 (requalified) — fatty-acid--CoA ligase FadD10 fadD10

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.