MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1427c · 42 genes shown · anchor lipO · open gene page → · ← back to 1 hop

Evidence: Min score 0
fadD12 (requalified) — acyl-CoA ligase FadD12 fadD12 lipO (family_assigned) — alpha/beta hydrolase lipO Rv1428c (family_assigned) — lysophospholipid acyltransferase family protein Rv1428c mbtE (requalified) — peptide synthetase mbtE rplF (requalified) — 50S ribosomal protein L6 rplF pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks12 (requalified) — type I polyketide synthase pks12 mas (requalified) — mycocerosate synthase mas ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC Rv1429 (family_assigned) — PucR family transcriptional regulator Rv1429 pks13 (requalified) — polyketide synthase Pks13 pks13 pks1 (requalified) — polyketide synthase pks1 Rv0310c (family_assigned) — nuclear transport factor 2 family protein Rv0310c rpmD (requalified) — 50S ribosomal protein L30 rpmD lepB (requalified) — signal peptidase I lepB galE2 (family_assigned) — SDR family oxidoreductase galE2 echA1 (family_assigned) — crotonase/enoyl-CoA hydratase family protein echA1 Rv1431 (family_assigned) — DUF3556 domain-containing protein Rv1431 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtC (requalified) — polyketide synthetase MbtC mbtC fas (requalified) — fatty acid synthase fas mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG rpsD (requalified) — 30S ribosomal protein S4 rpsD rplW (requalified) — 50S ribosomal protein L23 rplW rpsG (requalified) — 30S ribosomal protein S7 rpsG rplS (requalified) — 50S ribosomal protein L19 rplS rpsR1 (requalified) — 30S ribosomal protein S18 rpsR1 rplB (requalified) — 50S ribosomal protein L2 rplB fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD papA1 (requalified) — acyltransferase PapA1 papA1 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB Rv2113 (family_assigned) — integral membrane protein Rv2113 ptrp (family_assigned) — hypothetical protein ptrp nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 pks15 (requalified) — polyketide synthase pks15

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.