Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1381 · 25 genes shown · anchor pyrB · open gene page → · ← back to 1 hop

Evidence: Min score 0
pyrC (requalified) — dihydroorotase pyrC pyrB (family_assigned) — aspartate carbamoyltransferase catalytic subunit pyrB carA (family_assigned) — glutamine-hydrolyzing carbamoyl-phosphate synthase carA carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB pyrR (family_assigned) — bifunctional pyr operon transcriptional regulator/ pyrR Rv1382 (requalified) — transporter Rv1382 pyrD (requalified) — quinone-dependent dihydroorotate dehydrogenase pyrD pyrF (requalified) — orotidine-5'-phosphate decarboxylase pyrF pyrE (requalified) — orotate phosphoribosyltransferase pyrE ttfA (requalified) — trehalose monomycolate transport factor TtfA ttfA Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 Rv0385 (requalified) — FAD-binding oxidoreductase Rv0385 Rv1377c (requalified) — class I SAM-dependent methyltransferase Rv1377c argG (requalified) — argininosuccinate synthase argG Rv0381c (dark) — hypothetical protein Rv0381c prsA (requalified) — ribose-phosphate diphosphokinase prsA Rv1125 (family_assigned) — WS/DGAT domain-containing protein Rv1125 fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH fprB (requalified) — FAD-dependent oxidoreductase fprB fprA (requalified) — ferredoxin--NADP(+) reductase FprA fprA gltD (family_assigned) — glutamate synthase subunit beta gltD ephB (requalified) — epoxide hydrolase EphB ephB ribA1 (requalified) — riboflavin biosynthesis protein RibA ribA1 Rv1371 (family_assigned) — cytochrome b5 domain-containing protein Rv1371 Rv1378c (family_assigned) — hypothetical protein Rv1378c

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.