MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1349 · 45 genes shown · anchor irtA · open gene page → · ← back to 1 hop

Evidence: Min score 0
irtB (family_assigned) — iron ABC transporter ATP-binding protein/permease irtB irtA (family_assigned) — iron ABC transporter ATP-binding protein/permease irtA mbtE (requalified) — peptide synthetase mbtE mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA dnaK (requalified) — molecular chaperone DnaK dnaK Rv3402c (family_assigned) — DegT/DnrJ/EryC1/StrS family aminotransferase Rv3402c mbtB (requalified) — phenyloxazoline synthase MbtB mbtB Rv0435c (family_assigned) — AAA family ATPase Rv0435c mbtI (requalified) — salicylate synthase mbtI mbtF (requalified) — peptide synthetase mbtF Rv1687c (family_assigned) — ABC transporter ATP-binding protein Rv1687c fabG2 (requalified) — 3-oxoacyl-ACP reductase FabG fabG2 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtC (requalified) — polyketide synthetase MbtC mbtC fas (requalified) — fatty acid synthase fas mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD pks13 (requalified) — polyketide synthase Pks13 pks13 entC (requalified) — isochorismate synthase entC mbtJ (requalified) — acetyl hydrolase mbtJ clpB (requalified) — chaperone protein ClpB clpB dnaJ1 (requalified) — chaperone protein DnaJ dnaJ1 grpE (requalified) — nucleotide exchange factor GrpE grpE dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 hspR (family_assigned) — heat shock transcriptional regulator HspR hspR htpG (requalified) — molecular chaperone HtpG htpG mbtK (requalified) — lysine N-acyltransferase MbtK mbtK pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pssA (requalified) — CDP-diacylglycerol--serine O-phosphatidyltransfera pssA psd (requalified) — phosphatidylserine decarboxylase psd moeA2 (requalified) — molybdopterin molybdenumtransferase moeA2 prcB (family_assigned) — proteasome subunit beta prcB trpG (requalified) — anthranilate synthase component II trpG trpD (requalified) — anthranilate phosphoribosyltransferase trpD trpC (requalified) — indole-3-glycerol phosphate synthase TrpC trpC Rv1686c (family_assigned) — ABC transporter permease Rv1686c Rv1685c (family_assigned) — TetR family transcriptional regulator Rv1685c mpg (requalified) — DNA-3-methyladenine glycosylase mpg Rv1273c (family_assigned) — ABC transporter ATP-binding protein Rv1273c Rv1272c (family_assigned) — fatty acid ABC transporter ATP-binding protein/per Rv1272c fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD Rv3538 (requalified) — dehydrogenase Rv3538 htdY (requalified) — 3-hydroxyacyl-thioester dehydratase HtdY htdY Rv0769 (family_assigned) — SDR family oxidoreductase Rv0769 Rv3559c (family_assigned) — SDR family oxidoreductase Rv3559c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.