MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1345 · 40 genes shown · anchor mbtN · open gene page → · ← back to 1 hop

Evidence: Min score 0
mbtM (requalified) — long-chain-fatty acid--ACP ligase MbtM mbtM mbtN (requalified) — acyl-ACP dehydrogenase MbtN mbtN mbtL (requalified) — acyl carrier protein MbtL mbtL mbtE (requalified) — peptide synthetase mbtE mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtF (requalified) — peptide synthetase mbtF rplF (requalified) — 50S ribosomal protein L6 rplF pks12 (requalified) — type I polyketide synthase pks12 mas (requalified) — mycocerosate synthase mas pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks13 (requalified) — polyketide synthase Pks13 pks13 fadB (requalified) — fatty oxidation protein FadB fadB fixA (family_assigned) — electron transfer flavoprotein subunit beta/FixA f fixA fixB (family_assigned) — electron transfer flavoprotein subunit alpha/FixB fixB fadE18 (family_assigned) — acyl-CoA dehydrogenase family protein fadE18 fas (requalified) — fatty acid synthase fas acpM (requalified) — meromycolate extension acyl carrier protein AcpM acpM nuoC (family_assigned) — NADH-quinone oxidoreductase subunit C nuoC nuoB (family_assigned) — NADH-quinone oxidoreductase subunit B nuoB mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtC (requalified) — polyketide synthetase MbtC mbtC mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD rpsD (requalified) — 30S ribosomal protein S4 rpsD rplW (requalified) — 50S ribosomal protein L23 rplW rpsG (requalified) — 30S ribosomal protein S7 rpsG rplS (requalified) — 50S ribosomal protein L19 rplS rpsR1 (requalified) — 30S ribosomal protein S18 rpsR1 rplB (requalified) — 50S ribosomal protein L2 rplB fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD papA1 (requalified) — acyltransferase PapA1 papA1 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.