MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1296 · 46 genes shown · anchor thrC · open gene page → · ← back to 1 hop

Evidence: Min score 0
thrB (requalified) — homoserine kinase thrB thrC (requalified) — threonine synthase thrC thrA (requalified) — homoserine dehydrogenase thrA purM (requalified) — phosphoribosylformylglycinamidine cyclo-ligase purM sdaA (requalified) — L-serine ammonia-lyase sdaA ilvE (requalified) — branched-chain amino acid aminotransferase ilvE metH (requalified) — methionine synthase metH lysA (requalified) — diaminopimelate decarboxylase lysA metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ metB (requalified) — cystathionine gamma-synthase metB metC (requalified) — bifunctional o-acetylhomoserine/o-acetylserine sul metC metE (requalified) — 5-methyltetrahydropteroyltriglutamate--homocystein metE Rv0075 (family_assigned) — MalY/PatB family protein Rv0075 ilvA (requalified) — threonine ammonia-lyase ilvA serC (requalified) — phosphoserine transaminase serC argS (requalified) — arginine--tRNA ligase argS asd (requalified) — aspartate-semialdehyde dehydrogenase asd metA (requalified) — homoserine O-acetyltransferase metA dapA (requalified) — 4-hydroxy-tetrahydrodipicolinate synthase dapA purF (requalified) — amidophosphoribosyltransferase purF purQ (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purQ purN (requalified) — phosphoribosylglycinamide formyltransferase purN purD (requalified) — phosphoribosylamine--glycine ligase purD purL (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purL purK (requalified) — 5-(carboxyamino)imidazole ribonucleotide synthase purK glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 cbs (requalified) — cystathionine beta-synthase cbs trpA (family_assigned) — tryptophan synthase subunit alpha trpA serB2 (requalified) — phosphoserine phosphatase SerB serB2 ilvD (requalified) — dihydroxy-acid dehydratase ilvD leuA (requalified) — 2-isopropylmalate synthase leuA aspC (requalified) — pyridoxal phosphate-dependent aminotransferase aspC panB (requalified) — 3-methyl-2-oxobutanoate hydroxymethyltransferase panB gshA (requalified) — ergothioneine biosynthesis glutamate--cysteine lig gshA Rv2172c (requalified) — mycobacterial-type methylenetetrahydrofolate reduc Rv2172c sahH (requalified) — adenosylhomocysteinase sahH dapF (requalified) — diaminopimelate epimerase dapF murE (requalified) — UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-d murE dapB (requalified) — 4-hydroxy-tetrahydrodipicolinate reductase dapB cysK1 (requalified) — O-acetylserine sulfhydrylase cysK1 Rv3684 (requalified) — lyase Rv3684 Rv3342 (requalified) — class I SAM-dependent methyltransferase Rv3342 metK (requalified) — S-adenosylmethionine synthetase metK Rv0074 (family_assigned) — amidohydrolase family protein Rv0074 Rv2294 (family_assigned) — MalY/PatB family protein Rv2294

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.