MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1294 · 46 genes shown · anchor thrB · open gene page → · ← back to 1 hop

Evidence: Min score 0
thrA (requalified) — homoserine dehydrogenase thrA thrB (requalified) — homoserine kinase thrB thrC (requalified) — threonine synthase thrC asd (requalified) — aspartate-semialdehyde dehydrogenase asd metA (requalified) — homoserine O-acetyltransferase metA dapA (requalified) — 4-hydroxy-tetrahydrodipicolinate synthase dapA lysA (requalified) — diaminopimelate decarboxylase lysA metH (requalified) — methionine synthase metH ask (requalified) — aspartate kinase ask metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ argS (requalified) — arginine--tRNA ligase argS ilvE (requalified) — branched-chain amino acid aminotransferase ilvE metB (requalified) — cystathionine gamma-synthase metB purM (requalified) — phosphoribosylformylglycinamidine cyclo-ligase purM sdaA (requalified) — L-serine ammonia-lyase sdaA ilvA (requalified) — threonine ammonia-lyase ilvA serC (requalified) — phosphoserine transaminase serC dapF (requalified) — diaminopimelate epimerase dapF Rv3707c (requalified) — hypothetical protein Rv3707c dapB (requalified) — 4-hydroxy-tetrahydrodipicolinate reductase dapB metC (requalified) — bifunctional o-acetylhomoserine/o-acetylserine sul metC Rv3342 (requalified) — class I SAM-dependent methyltransferase Rv3342 rnj (requalified) — ribonuclease J rnj thyX (requalified) — FAD-dependent thymidylate synthase thyX murE (requalified) — UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2%2C6-d murE Rv2172c (requalified) — mycobacterial-type methylenetetrahydrofolate reduc Rv2172c metE (requalified) — 5-methyltetrahydropteroyltriglutamate--homocystein metE sahH (requalified) — adenosylhomocysteinase sahH asnB (requalified) — asparagine synthase (glutamine-hydrolyzing) asnB purA (requalified) — adenylosuccinate synthase purA argG (requalified) — argininosuccinate synthase argG nadB (requalified) — L-aspartate oxidase nadB cbs (requalified) — cystathionine beta-synthase cbs cysK1 (requalified) — O-acetylserine sulfhydrylase cysK1 Rv3684 (requalified) — lyase Rv3684 guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA gltS (requalified) — glutamate--tRNA ligase gltS ileS (requalified) — isoleucine--tRNA ligase ileS metS (requalified) — methionine--tRNA ligase metS proS (requalified) — proline--tRNA ligase proS leuS (requalified) — leucine--tRNA ligase leuS ilvD (requalified) — dihydroxy-acid dehydratase ilvD leuA (requalified) — 2-isopropylmalate synthase leuA aspC (requalified) — pyridoxal phosphate-dependent aminotransferase aspC panB (requalified) — 3-methyl-2-oxobutanoate hydroxymethyltransferase panB gshA (requalified) — ergothioneine biosynthesis glutamate--cysteine lig gshA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.