MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1265 · 46 genes shown · anchor rsfB · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1265 (family_assigned) — hypothetical protein Rv1265 rsfB (family_assigned) — STAS domain-containing protein rsfB Rv1362c (family_assigned) — hypothetical protein Rv1362c Rv0898c (family_assigned) — DUF2630 family protein Rv0898c Rv1264 (requalified) — adenylate cyclase Rv1264 Rv2390c (family_assigned) — hypothetical protein Rv2390c Rv3492c (requalified) — Mce associated protein Rv3492c lppW (family_assigned) — hypothetical protein lppW amiB2 (requalified) — amidase amiB2 mctB (requalified) — copper transporter MctB mctB Rv2226 (family_assigned) — CYTH and CHAD domain-containing protein Rv2226 lprN (family_assigned) — Mce family lipoprotein LprN lprN tuf (requalified) — elongation factor Tu tuf Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c rsbW (requalified) — anti-sigma B factor RsbW rsbW Rv1354c (requalified) — bifunctional diguanylate cyclase/phosphodiesterase Rv1354c fbiC (requalified) — bifunctional FO biosynthesis protein CofGH fbiC mkl (family_assigned) — ABC transporter ATP-binding protein mkl Rv0258c (requalified) — hypothetical protein Rv0258c Rv1363c (dark) — hypothetical protein Rv1363c mce2F (family_assigned) — MlaD family protein mce2F mce1D (family_assigned) — virulence factor Mce family protein mce1D mce1A (family_assigned) — Mce family protein Mce1A mce1A mce1F (family_assigned) — MCE family protein mce1F mce4A (family_assigned) — Mce family protein Mce4A mce4A Rv0897c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0897c arfA (family_assigned) — peptidoglycan-binding protein ArfA arfA arfC (family_assigned) — hypothetical protein arfC arfB (family_assigned) — hypothetical protein arfB pykA (requalified) — pyruvate kinase pykA ndkA (requalified) — nucleoside-diphosphate kinase ndkA cpdA (requalified) — 3'%2C5'-cyclic adenosine monophosphate phosphodies cpdA relA (family_assigned) — RelA/SpoT family protein relA ribA2 (requalified) — bifunctional 3%2C4-dihydroxy-2-butanone-4-phosphat ribA2 rpfD (requalified) — resuscitation-promoting factor protein RpfD rpfD pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks12 (requalified) — type I polyketide synthase pks12 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC mce4D (family_assigned) — virulence factor Mce family protein mce4D mce4F (family_assigned) — virulence factor Mce family protein mce4F Rv3493c (requalified) — mammalian cell entry protein Rv3493c mce4C (family_assigned) — virulence factor Mce family protein mce4C Rv1836c (family_assigned) — substrate-binding domain-containing protein Rv1836c Rv3906c (requalified) — pullulanase Rv3906c eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.