MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1223 · 46 genes shown · anchor tatB · open gene page → · ← back to 1 hop

Evidence: Min score 0
htrA (requalified) — serine protease HtrA htrA tatB (requalified) — Sec-independent protein translocase protein TatB tatB mpa (requalified) — proteasome ATPase mpa rseA (requalified) — anti-sigma E factor RseA rseA glpK (requalified) — glycerol kinase GlpK glpK mec (requalified) — CysO-cysteine peptidase mec prcB (family_assigned) — proteasome subunit beta prcB prcA (family_assigned) — proteasome subunit alpha prcA alaS (requalified) — alanine--tRNA ligase alaS oxcA (requalified) — oxalyl-CoA decarboxylase oxcA pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 Rv2609c (family_assigned) — NUDIX domain-containing protein Rv2609c mas (requalified) — mycocerosate synthase mas guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA tatC (family_assigned) — twin-arginine translocase subunit TatC tatC Rv1337 (family_assigned) — rhomboid family intramembrane serine protease Rv1337 sigE (requalified) — RNA polymerase sigma factor SigE sigE pup (family_assigned) — ubiquitin-like protein Pup pup bpa (requalified) — proteasome activator protein Bpa bpa Rv1109c (requalified) — lipid droplet-associated protein Rv1109c Rv2520c (dark) — DUF3618 domain-containing protein Rv2520c Rv1083 (dark) — hypothetical protein Rv1083 glpD2 (requalified) — glycerol-3-phosphate dehydrogenase/oxidase glpD2 glpD1 (requalified) — glycerol-3-phosphate dehydrogenase/oxidase glpD1 cysM (requalified) — O-phosphoserine sulfhydrylase cysM cysO (requalified) — sulfur carrier protein CysO cysO rpsC (requalified) — 30S ribosomal protein S3 rpsC rpsS (requalified) — 30S ribosomal protein S19 rpsS dop (requalified) — pup deamidase/depupylase dop pafA (requalified) — Pup--protein ligase pafA ruvX (requalified) — Holliday junction resolvase RuvX ruvX mltG (requalified) — endolytic transglycosylase MltG mltG Rv1691 (family_assigned) — hypothetical protein Rv1691 Rv3529c (requalified) — TLR2-mediated response inhibitor Rv3529c Rv2267c (requalified) — sulfotransferase Rv2267c aroE (requalified) — shikimate dehydrogenase aroE ilvN (family_assigned) — acetolactate synthase small subunit ilvN fadD7 (family_assigned) — FadD7 family fatty acid--CoA ligase fadD7 ilvC (requalified) — ketol-acid reductoisomerase ilvC ilvD (requalified) — dihydroxy-acid dehydratase ilvD leuA (requalified) — 2-isopropylmalate synthase leuA fas (requalified) — fatty acid synthase fas fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD mbtB (requalified) — phenyloxazoline synthase MbtB mbtB pks12 (requalified) — type I polyketide synthase pks12 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.