MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1186c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1186c (family_assigned) — PucR family transcriptional regulator Rv1186c Rv1188 (requalified) — proline dehydrogenase Rv1188 rocA (requalified) — L-glutamate gamma-semialdehyde dehydrogenase rocA moaR1 (family_assigned) — transcriptional regulator MoaR1 moaR1 Rv3055 (family_assigned) — helix-turn-helix domain-containing protein Rv3055 Rv2474c (family_assigned) — hypothetical protein Rv2474c fadD21 (requalified) — fatty-acid--AMP ligase FAAL21/FadD21 fadD21 embR (requalified) — response regulator transcription factor EmbR embR eccE1 (family_assigned) — type VII secretion system ESX-1 subunit EccE1 eccE1 Rv0513 (family_assigned) — DUF3093 domain-containing protein Rv0513 Rv1171 (family_assigned) — hypothetical protein Rv1171 Rv1191 (family_assigned) — alpha/beta hydrolase Rv1191 Rv1871c (family_assigned) — nitroreductase family deazaflavin-dependent oxidor Rv1871c proC (requalified) — pyrroline-5-carboxylate reductase proC pip (family_assigned) — proline-specific peptidase family protein pip aldC (requalified) — aldehyde dehydrogenase AldC aldC Rv1249c (family_assigned) — hypothetical protein Rv1249c rocD1 (family_assigned) — Probable ornithine aminotransferase (N-terminus pa rocD1 gltB (family_assigned) — glutamate synthase large subunit gltB gadB (requalified) — glutamate decarboxylase gadB gltD (family_assigned) — glutamate synthase subunit beta gltD gdh (requalified) — NAD-glutamate dehydrogenase gdh Rv0894 (family_assigned) — hypothetical protein Rv0894 Rv3830c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3830c iniR (family_assigned) — isoniazid response ATPase/transcriptional regulato iniR Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 Rv3840 (family_assigned) — transcriptional regulator Rv3840 dinP (requalified) — DNA polymerase IV dinP Rv1725c (family_assigned) — winged helix-turn-helix transcriptional regulator Rv1725c Rv0737 (family_assigned) — MarR family transcriptional regulator Rv0737 Rv1167c (family_assigned) — TetR/AcrR family transcriptional regulator Rv1167c Rv2475c (family_assigned) — thioesterase family protein Rv2475c ettA (requalified) — energy-dependent translational throttle protein Et ettA Rv3438 (family_assigned) — alpha/beta hydrolase Rv3438 Rv2446c (dark) — DUF4233 domain-containing protein Rv2446c Rv0358 (requalified) — peptidase M50 Rv0358 mbtE (requalified) — peptide synthetase mbtE pks15 (requalified) — polyketide synthase pks15 pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 pks6 (requalified) — membrane bound polyketide synthase pks6 ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c mce3R (family_assigned) — TetR family transcriptional regulator Mce3R mce3R mftR (family_assigned) — mycofactocin system transcriptional regulator mftR mycP1 (requalified) — type VII secretion system ESX-1 serine protease my mycP1

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.