MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1181 · 38 genes shown · anchor fas · open gene page → · ← back to 1 hop

Evidence: Min score 0
pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 fas (requalified) — fatty acid synthase fas pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 papA3 (requalified) — acyltransferase PapA3 papA3 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB pks15 (requalified) — polyketide synthase pks15 fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp pks12 (requalified) — type I polyketide synthase pks12 mbtC (requalified) — polyketide synthetase MbtC mbtC mas (requalified) — mycocerosate synthase mas pks7 (requalified) — type I polyketide synthase pks7 pks17 (requalified) — polyketide synthase pks17 accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 pks6 (requalified) — membrane bound polyketide synthase pks6 pks1 (requalified) — polyketide synthase pks1 Rv3777 (requalified) — oxidoreductase Rv3777 fadB4 (family_assigned) — NADPH:quinone oxidoreductase family protein fadB4 mmpL10 (requalified) — RND transporter MmpL10 mmpL10 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB papA1 (requalified) — acyltransferase PapA1 papA1 mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtE (requalified) — peptide synthetase mbtE fadD29 (requalified) — long-chain-fatty-acid--AMP ligase FadD29 fadD29 fadD22 (requalified) — p-hydroxybenzoic acid--AMP ligase FadD22 fadD22 Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c kasA (requalified) — 3-oxoacyl-ACP synthase KasA kasA kasB (requalified) — 3-oxoacyl-ACP synthase 2 kasB fadD10 (requalified) — fatty-acid--CoA ligase FadD10 fadD10 mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD mbtF (requalified) — peptide synthetase mbtF

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.