Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1173 · 46 genes shown · anchor fbiA · open gene page → · ← back to 1 hop

Evidence: Min score 0
fbiC (requalified) — bifunctional FO biosynthesis protein CofGH fbiC Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c fbiA (requalified) — 2-phospho-L-lactate transferase fbiA thiG (requalified) — thiazole synthase thiG thiC (requalified) — phosphomethylpyrimidine synthase ThiC thiC thiE (requalified) — thiamine phosphate synthase thiE rsbW (requalified) — anti-sigma B factor RsbW rsbW thiS (requalified) — sulfur carrier protein ThiS thiS Rv1354c (requalified) — bifunctional diguanylate cyclase/phosphodiesterase Rv1354c PE12 (family_assigned) — PE family protein PE12 PE12 fbiB (requalified) — coenzyme F420-0:L-glutamate ligase fbiB rsfB (family_assigned) — STAS domain-containing protein rsfB Rv1904 (requalified) — anti-sigma factor antagonist Rv1904 rsfA (requalified) — anti-sigma-F factor antagonist RsfA rsfA Rv2638 (requalified) — anti-sigma factor antagonist Rv2638 cofC (requalified) — 2-phospho-L-lactate guanylyltransferase cofC ddn (requalified) — deazaflavin-dependent nitroreductase Ddn ddn fgd2 (requalified) — F420-dependent hydroxymycolic acid dehydrogenase fgd2 Rv3178 (requalified) — nitroreductase Rv3178 thiO (requalified) — glycine oxidase ThiO thiO cysO (requalified) — sulfur carrier protein CysO cysO dxs2 (requalified) — 1-deoxy-D-xylulose-5-phosphate synthase dxs2 thiD (requalified) — hydroxymethylpyrimidine/phosphomethylpyrimidine ki thiD Rv0421c (family_assigned) — alpha/beta family hydrolase Rv0421c thiL (requalified) — thiamine-phosphate kinase thiL rsgA (family_assigned) — ribosome small subunit-dependent GTPase A rsgA sigF (requalified) — RNA polymerase sigma factor SigF sigF usfY (family_assigned) — hypothetical protein usfY mec (requalified) — CysO-cysteine peptidase mec mesJ (requalified) — tRNA lysidine(34) synthetase TilS mesJ moeY (family_assigned) — Rv1355c family protein moeY Rv1353c (family_assigned) — TetR/AcrR family transcriptional regulator C-termi Rv1353c Rv1356c (requalified) — hypothetical protein Rv1356c Rv1358 (family_assigned) — LuxR C-terminal-related transcriptional regulator Rv1358 Rv1357c (requalified) — cyclic diguanylate phosphodiesterase Rv1357c vapB28 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB28 nuoI (family_assigned) — NADH-quinone oxidoreductase subunit NuoI nuoI hsdM (requalified) — class I SAM-dependent DNA methyltransferase hsdM ctaE (family_assigned) — heme-copper oxidase subunit III ctaE eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 Rv3520c (requalified) — coenzyme F420-dependent oxidoreductase Rv3520c Rv3093c (requalified) — LLM class F420-dependent oxidoreductase Rv3093c Rv3300c (family_assigned) — RluA family pseudouridine synthase Rv3300c mkl (family_assigned) — ABC transporter ATP-binding protein mkl Rv0258c (requalified) — hypothetical protein Rv0258c Rv1752 (family_assigned) — hypothetical protein Rv1752

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.