MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1152 · 46 genes shown · anchor cobB · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1152 (family_assigned) — GntR family transcriptional regulator Rv1152 cobB (requalified) — NAD-dependent protein deacylase cobB Rv1019 (family_assigned) — TetR/AcrR family transcriptional regulator Rv1019 Rv1725c (family_assigned) — winged helix-turn-helix transcriptional regulator Rv1725c embR (requalified) — response regulator transcription factor EmbR embR mftR (family_assigned) — mycofactocin system transcriptional regulator mftR Rv0038 (family_assigned) — YqgE/AlgH family protein Rv0038 Rv1931c (family_assigned) — transcriptional regulator Rv1931c sirR (family_assigned) — manganese-binding transcriptional regulator MntR sirR nadR (requalified) — nicotinamide-nucleotide adenylyltransferase nadR Rv0275c (family_assigned) — transcriptional regulator Rv0275c Rv1985c (family_assigned) — ArgP/LysG family DNA-binding transcriptional regul Rv1985c Rv1674c (family_assigned) — metalloregulator ArsR/SmtB family transcription fa Rv1674c nadE (requalified) — NAD(+) synthase nadE pncA (requalified) — pyrazinamidase PncA pncA nadD (requalified) — nicotinate-nucleotide adenylyltransferase nadD sthA (requalified) — Si-specific NAD(P)(+) transhydrogenase sthA Rv0653c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0653c Rv1724c (dark) — hypothetical protein Rv1724c sigI (requalified) — RNA polymerase sigma factor SigI sigI Rv3055 (family_assigned) — helix-turn-helix domain-containing protein Rv3055 Rv3167c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3167c sigJ (family_assigned) — sigma-70 family RNA polymerase sigma factor SigJ sigJ Rv0894 (family_assigned) — hypothetical protein Rv0894 Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c iniR (family_assigned) — isoniazid response ATPase/transcriptional regulato iniR Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 mce3R (family_assigned) — TetR family transcriptional regulator Mce3R mce3R Rv3830c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3830c mftB (requalified) — mycofactocin biosynthesis chaperone MftB mftB mftC (requalified) — mycofactocin radical SAM maturase mftC Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 Rv0690c (family_assigned) — DUF2332 domain-containing protein Rv0690c nrdE (family_assigned) — ribonucleoside-diphosphate reductase subunit alpha nrdE nrdZ (requalified) — adenosylcobalamin-dependent ribonucleoside-diphosp nrdZ Rv1359 (family_assigned) — transcriptional regulator Rv1359 Rv1488 (family_assigned) — SPFH domain-containing protein Rv1488 Rv1930c (requalified) — glutamine amidotransferase Rv1930c virS (family_assigned) — AraC family transcriptional regulator virS Rv3736 (family_assigned) — AraC family transcriptional regulator Rv3736 Rv3066 (family_assigned) — TetR/AcrR family transcriptional regulator Rv3066 Rv0273c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0273c ppnK (requalified) — NAD kinase ppnK pncB2 (requalified) — nicotinate phosphoribosyltransferase pncB2 pncB1 (requalified) — nicotinate phosphoribosyltransferase pncB1 cinA (requalified) — competence/damage-inducible protein A cinA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.