MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1127c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
ppdK (requalified) — pyruvate%2C phosphate dikinase ppdK Rv1126c (family_assigned) — MarR family transcriptional regulator Rv1126c Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c mez (requalified) — NAD-dependent malic enzyme mez eno (requalified) — phosphopyruvate hydratase eno pca (requalified) — pyruvate carboxylase pca Rv2454c (family_assigned) — 2-oxoacid:ferredoxin oxidoreductase subunit beta Rv2454c bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB bkdA (family_assigned) — pyruvate dehydrogenase (acetyl-transferring) E1 co bkdA pykA (requalified) — pyruvate kinase pykA aceE (requalified) — pyruvate dehydrogenase E1 component aceE mftD (requalified) — pre-mycofactocin synthase MftD mftD pckA (requalified) — phosphoenolpyruvate carboxykinase (GTP) pckA Rv1868 (family_assigned) — NAD(P)H-binding protein Rv1868 Rv0219 (dark) — hypothetical protein Rv0219 Rv2047c (family_assigned) — sugar epimerase family protein Rv2047c Rv1006 (family_assigned) — hypothetical protein Rv1006 Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c icd2 (requalified) — NADP-dependent isocitrate dehydrogenase icd2 aroF (requalified) — chorismate synthase aroF pta (requalified) — phosphate acetyltransferase pta sucD (family_assigned) — succinyl-CoA ligase subunit alpha sucD sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC mdh (requalified) — malate dehydrogenase mdh fum (requalified) — class II fumarate hydratase fum glcB (requalified) — malate synthase G glcB pgk (requalified) — phosphoglycerate kinase pgk gpm1 (requalified) — 2,3-bisphosphoglycerate-dependent phosphoglycerate gpm1 pgi (requalified) — glucose-6-phosphate isomerase pgi gap (requalified) — type I glyceraldehyde-3-phosphate dehydrogenase gap fba (requalified) — class II fructose-bisphosphate aldolase fba prpC (requalified) — 2-methylcitrate synthase prpC gltA2 (requalified) — citrate synthase gltA2 citA (requalified) — citrate synthase 2 citA mobA (requalified) — molybdenum cofactor guanylyltransferase mobA bkdC (family_assigned) — dihydrolipoamide acetyltransferase family protein bkdC Rv0843 (family_assigned) — thiamine pyrophosphate-dependent dehydrogenase E1 Rv0843 Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC dlaT (requalified) — 2-oxoglutarate dehydrogenase%2C E2 component%2C di dlaT rplJ (requalified) — 50S ribosomal protein L10 rplJ rplX (requalified) — 50S ribosomal protein L24 rplX rplB (requalified) — 50S ribosomal protein L2 rplB rplE (requalified) — 50S ribosomal protein L5 rplE rplF (requalified) — 50S ribosomal protein L6 rplF mftC (requalified) — mycofactocin radical SAM maturase mftC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.