MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1109c · 44 genes shown · anchor xseA · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv1109c (requalified) — lipid droplet-associated protein Rv1109c xseA (family_assigned) — exodeoxyribonuclease VII large subunit xseA xseB (family_assigned) — exodeoxyribonuclease VII small subunit xseB Rv1106c (requalified) — 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-is Rv1106c lytB2 (requalified) — 4-hydroxy-3-methylbut-2-enyl diphosphate reductase lytB2 Rv2091c (family_assigned) — DUF4333 domain-containing protein Rv2091c Rv3850 (family_assigned) — DUF6474 family protein Rv3850 Rv3311 (family_assigned) — primosomal protein Rv3311 Rv3212 (family_assigned) — hypothetical protein Rv3212 Rv0556 (family_assigned) — DUF3592 domain-containing protein Rv0556 Rv2732c (family_assigned) — hypothetical protein Rv2732c Rv2446c (dark) — DUF4233 domain-containing protein Rv2446c Rv3205c (family_assigned) — hypothetical protein Rv3205c folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD nusG (requalified) — transcription termination/antitermination protein nusG hemC (requalified) — hydroxymethylbilane synthase hemC rbpA (family_assigned) — RNA polymerase-binding protein RbpA rbpA cyp142 (requalified) — steroid C26-monooxygenase Cyp142 cyp142 cyp125 (requalified) — steroid C26-monooxygenase cyp125 choD (requalified) — cholesterol oxidase choD gcpE (requalified) — flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-e gcpE rpsA (requalified) — 30S ribosomal protein S1 rpsA Rv3382c (requalified) — 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Rv3382c idsA2 (requalified) — bifunctional (2E%2C6E)-farnesyl/geranyl diphosphat idsA2 idsA1 (requalified) — multifunctional dimethylallyltransferase/geranyltr idsA1 idsB (family_assigned) — polyprenyl synthetase family protein idsB cei (requalified) — envelope integrity protein Cei cei Rv2520c (dark) — DUF3618 domain-containing protein Rv2520c Rv3851 (dark) — hypothetical protein Rv3851 espR (family_assigned) — type VII secretion system ESX-1 transcriptional re espR Rv3438 (family_assigned) — alpha/beta hydrolase Rv3438 sapM (requalified) — phosphatidylinositol-3-phosphatase sapM rhlE (requalified) — DEAD/DEAH box helicase rhlE lppL (family_assigned) — hypothetical protein lppL menD (requalified) — 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1 menD bpoC (family_assigned) — alpha/beta hydrolase bpoC mgtA (requalified) — GDP-mannose-dependent alpha-mannosyltransferase mgtA Rv1632c (family_assigned) — DUF402 domain-containing protein Rv1632c miaB (requalified) — tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiot miaB folC (requalified) — bifunctional tetrahydrofolate synthase/dihydrofola folC valS (requalified) — valine--tRNA ligase valS Rv0863 (family_assigned) — hypothetical protein Rv0863 moeB1 (requalified) — adenylyltransferase/sulfurtransferase MoeZ moeB1 Rv0358 (requalified) — peptidase M50 Rv0358

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.