MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1077 · 41 genes shown · anchor metB · open gene page → · ← back to 1 hop

Evidence: Min score 0
cbs (requalified) — cystathionine beta-synthase cbs metB (requalified) — cystathionine gamma-synthase metB metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ cysE (requalified) — serine O-acetyltransferase cysE sahH (requalified) — adenosylhomocysteinase sahH glyA1 (requalified) — serine hydroxymethyltransferase glyA1 glyA2 (requalified) — serine hydroxymethyltransferase glyA2 metC (requalified) — bifunctional o-acetylhomoserine/o-acetylserine sul metC ilvA (requalified) — threonine ammonia-lyase ilvA metH (requalified) — methionine synthase metH serB2 (requalified) — phosphoserine phosphatase SerB serB2 metE (requalified) — 5-methyltetrahydropteroyltriglutamate--homocystein metE trpA (family_assigned) — tryptophan synthase subunit alpha trpA cysK1 (requalified) — O-acetylserine sulfhydrylase cysK1 Rv3684 (requalified) — lyase Rv3684 sdaA (requalified) — L-serine ammonia-lyase sdaA cysS1 (requalified) — cysteine--tRNA ligase cysS1 mtn (requalified) — 5'-methylthioadenosine/adenosylhomocysteine nucleo mtn gcvB (requalified) — aminomethyl-transferring glycine dehydrogenase gcvB gcvT (requalified) — aminomethyltransferase gcvT purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD purN (requalified) — phosphoribosylglycinamide formyltransferase purN gcvH (requalified) — glycine cleavage system protein GcvH gcvH metA (requalified) — homoserine O-acetyltransferase metA Rv3342 (requalified) — class I SAM-dependent methyltransferase Rv3342 ilvN (family_assigned) — acetolactate synthase small subunit ilvN ilvB1 (family_assigned) — acetolactate synthase large subunit IlvB ilvB1 leuB (requalified) — 3-isopropylmalate dehydrogenase leuB thrC (requalified) — threonine synthase thrC ilvB2 (family_assigned) — thiamine pyrophosphate-binding protein ilvB2 ilvG (requalified) — acetolactate synthase ilvG Rv2172c (requalified) — mycobacterial-type methylenetetrahydrofolate reduc Rv2172c serC (requalified) — phosphoserine transaminase serC trpB (family_assigned) — tryptophan synthase subunit beta trpB metK (requalified) — S-adenosylmethionine synthetase metK trpC (requalified) — indole-3-glycerol phosphate synthase TrpC trpC lgt (requalified) — prolipoprotein diacylglyceryl transferase lgt trpE (requalified) — anthranilate synthase component I trpE trpD (requalified) — anthranilate phosphoribosyltransferase trpD trpG (requalified) — anthranilate synthase component II trpG

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.