MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1058 · 38 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
fadD14 (requalified) — long-chain fatty acid--CoA ligase fadD14 Rv1059 (requalified) — dihydrodipicolinate reductase Rv1059 Rv1060 (family_assigned) — SRPBCC family protein Rv1060 Rv1057 (family_assigned) — YncE family protein Rv1057 Rv1062 (family_assigned) — patatin-like phospholipase family protein Rv1062 Rv1061 (requalified) — class II glutamine amidotransferase Rv1061 rplF (requalified) — 50S ribosomal protein L6 rplF pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks12 (requalified) — type I polyketide synthase pks12 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC mas (requalified) — mycocerosate synthase mas pks13 (requalified) — polyketide synthase Pks13 pks13 Rv0926c (requalified) — diacylglycerol kinase Rv0926c aao (requalified) — FAD-dependent oxidoreductase aao PE_PGRS42 (family_assigned) — PE-PGRS family protein PE_PGRS42 PE_PGRS42 Rv3899c (family_assigned) — hypothetical protein Rv3899c PE_PGRS17 (family_assigned) — PE-PGRS family protein PE_PGRS17 PE_PGRS17 PE_PGRS18 (family_assigned) — PE-PGRS family protein PE_PGRS18 PE_PGRS18 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB Rv0941c (family_assigned) — STAS domain-containing protein Rv0941c Rv0232 (family_assigned) — TetR/AcrR family transcriptional regulator Rv0232 rpsD (requalified) — 30S ribosomal protein S4 rpsD rplW (requalified) — 50S ribosomal protein L23 rplW rpsG (requalified) — 30S ribosomal protein S7 rpsG rplS (requalified) — 50S ribosomal protein L19 rplS rpsR1 (requalified) — 30S ribosomal protein S18 rpsR1 rplB (requalified) — 50S ribosomal protein L2 rplB fas (requalified) — fatty acid synthase fas fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD papA1 (requalified) — acyltransferase PapA1 papA1 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.