MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv1013 · 44 genes shown · anchor mbtE · open gene page → · ← back to 1 hop

Evidence: Min score 0
pks16 (requalified) — fatty acyl-AMP ligase pks16 mbtE (requalified) — peptide synthetase mbtE mbtF (requalified) — peptide synthetase mbtF Rv1592c (family_assigned) — lipase family protein Rv1592c ispE (requalified) — 4-diphosphocytidyl-2C-methyl-D-erythritol kinase ispE rplF (requalified) — 50S ribosomal protein L6 rplF pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks12 (requalified) — type I polyketide synthase pks12 mas (requalified) — mycocerosate synthase mas pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks13 (requalified) — polyketide synthase Pks13 pks13 nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtC (requalified) — polyketide synthetase MbtC mbtC fas (requalified) — fatty acid synthase fas mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD cfp21 (requalified) — cutinase Cfp21 cfp21 cut3 (family_assigned) — cutinase family protein cut3 cut4 (requalified) — cutinase Cut4 cut4 Rv1593c (family_assigned) — NUDIX domain-containing protein Rv1593c cut2 (family_assigned) — cutinase family protein cut2 ispF (requalified) — 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate syn ispF ispD (requalified) — 2-C-methyl-D-erythritol 4-phosphate cytidylyltrans ispD ksgA (requalified) — 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-d ksgA dxr (requalified) — 1-deoxy-D-xylulose-5-phosphate reductoisomerase dxr gcpE (requalified) — flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-e gcpE lytB2 (requalified) — 4-hydroxy-3-methylbut-2-enyl diphosphate reductase lytB2 rpsD (requalified) — 30S ribosomal protein S4 rpsD rplW (requalified) — 50S ribosomal protein L23 rplW rpsG (requalified) — 30S ribosomal protein S7 rpsG rplS (requalified) — 50S ribosomal protein L19 rplS rpsR1 (requalified) — 30S ribosomal protein S18 rpsR1 rplB (requalified) — 50S ribosomal protein L2 rplB fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD papA1 (requalified) — acyltransferase PapA1 papA1 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 fadD10 (requalified) — fatty-acid--CoA ligase FadD10 fadD10

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.