MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0957 · 35 genes shown · anchor purN · open gene page → · ← back to 1 hop

Evidence: Min score 0
purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH purN (requalified) — phosphoribosylglycinamide formyltransferase purN purB (requalified) — adenylosuccinate lyase purB glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 purT (requalified) — phosphoribosylglycinamide formyltransferase 2 purT purA (requalified) — adenylosuccinate synthase purA folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD purD (requalified) — phosphoribosylamine--glycine ligase purD purF (requalified) — amidophosphoribosyltransferase purF purM (requalified) — phosphoribosylformylglycinamidine cyclo-ligase purM apt (requalified) — adenine phosphoribosyltransferase apt guaB2 (requalified) — IMP dehydrogenase guaB2 purQ (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purQ purL (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purL Rv0787A (family_assigned) — hypothetical protein Rv0787A purC (requalified) — phosphoribosylaminoimidazolesuccinocarboxamide syn purC adk (requalified) — adenylate kinase adk fas (requalified) — fatty acid synthase fas sdaA (requalified) — L-serine ammonia-lyase sdaA gcvB (requalified) — aminomethyl-transferring glycine dehydrogenase gcvB gcvT (requalified) — aminomethyltransferase gcvT gcvH (requalified) — glycine cleavage system protein GcvH gcvH guaB1 (family_assigned) — GuaB1 family IMP dehydrogenase-related protein guaB1 guaB3 (family_assigned) — GuaB3 family IMP dehydrogenase-related protein guaB3 Rv0356c (family_assigned) — PaaI family thioesterase Rv0356c fmt (requalified) — methionyl-tRNA formyltransferase fmt purE (requalified) — 5-(carboxyamino)imidazole ribonucleotide mutase purE carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB purK (requalified) — 5-(carboxyamino)imidazole ribonucleotide synthase purK guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA gmk (requalified) — guanylate kinase gmk deoD (requalified) — purine-nucleoside phosphorylase deoD adoK (family_assigned) — carbohydrate kinase family protein adoK rdgB (family_assigned) — RdgB/HAM1 family non-canonical purine NTP pyrophos rdgB

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.