MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0808 · 39 genes shown · anchor purM · open gene page → · ← back to 1 hop

Evidence: Min score 0
purF (requalified) — amidophosphoribosyltransferase purF purM (requalified) — phosphoribosylformylglycinamidine cyclo-ligase purM purD (requalified) — phosphoribosylamine--glycine ligase purD purQ (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purQ purL (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purL carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH purN (requalified) — phosphoribosylglycinamide formyltransferase purN carA (family_assigned) — glutamine-hydrolyzing carbamoyl-phosphate synthase carA purE (requalified) — 5-(carboxyamino)imidazole ribonucleotide mutase purE gltB (family_assigned) — glutamate synthase large subunit gltB prsA (requalified) — ribose-phosphate diphosphokinase prsA purB (requalified) — adenylosuccinate lyase purB purK (requalified) — 5-(carboxyamino)imidazole ribonucleotide synthase purK purC (requalified) — phosphoribosylaminoimidazolesuccinocarboxamide syn purC Rv0787A (family_assigned) — hypothetical protein Rv0787A purT (requalified) — phosphoribosylglycinamide formyltransferase 2 purT pyrB (family_assigned) — aspartate carbamoyltransferase catalytic subunit pyrB pyrC (requalified) — dihydroorotase pyrC pyrF (requalified) — orotidine-5'-phosphate decarboxylase pyrF Rv1382 (requalified) — transporter Rv1382 argG (requalified) — argininosuccinate synthase argG glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 purA (requalified) — adenylosuccinate synthase purA pyrR (family_assigned) — bifunctional pyr operon transcriptional regulator/ pyrR gltD (family_assigned) — glutamate synthase subunit beta gltD fprA (requalified) — ferredoxin--NADP(+) reductase FprA fprA fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH fprB (requalified) — FAD-dependent oxidoreductase fprB glnA1 (requalified) — type I glutamate--ammonia ligase glnA1 bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c glmU (requalified) — bifunctional UDP-N-acetylglucosamine diphosphoryla glmU tkt (requalified) — transketolase tkt rbsK (requalified) — ribokinase RbsK rbsK apt (requalified) — adenine phosphoribosyltransferase apt adk (requalified) — adenylate kinase adk fas (requalified) — fatty acid synthase fas

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.