MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0764c · 37 genes shown · anchor cyp123 · open gene page → · ← back to 1 hop

Evidence: Min score 0
cyp51 (requalified) — lanosterol 14-alpha demethylase cyp51 cyp123 (requalified) — cytochrome P450 cyp123 Rv0762c (family_assigned) — nuclear transport factor 2 family protein Rv0762c Rv0763c (requalified) — ferredoxin Rv0763c Rv0765c (family_assigned) — SDR family oxidoreductase Rv0765c Rv0767c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0767c Rv0770 (requalified) — NAD(P)-dependent oxidoreductase Rv0770 Rv0771 (family_assigned) — carboxymuconolactone decarboxylase family protein Rv0771 aldA (requalified) — aldehyde dehydrogenase aldA pks13 (requalified) — polyketide synthase Pks13 pks13 mbtE (requalified) — peptide synthetase mbtE Rv0769 (family_assigned) — SDR family oxidoreductase Rv0769 Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 Rv3167c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3167c purD (requalified) — phosphoribosylamine--glycine ligase purD adhB (requalified) — alcohol dehydrogenase B adhB acs (requalified) — acetate--CoA ligase acs mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 mbtC (requalified) — polyketide synthetase MbtC mbtC mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD htdY (requalified) — 3-hydroxyacyl-thioester dehydratase HtdY htdY Rv3559c (family_assigned) — SDR family oxidoreductase Rv3559c fabG2 (requalified) — 3-oxoacyl-ACP reductase FabG fabG2 Rv3538 (requalified) — dehydrogenase Rv3538 fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH fprB (requalified) — FAD-dependent oxidoreductase fprB fprA (requalified) — ferredoxin--NADP(+) reductase FprA fprA gltD (family_assigned) — glutamate synthase subunit beta gltD ephB (requalified) — epoxide hydrolase EphB ephB ribA1 (requalified) — riboflavin biosynthesis protein RibA ribA1

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.