Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0756c · 46 genes shown · anchor phoP · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0756c (family_assigned) — hypothetical protein Rv0756c phoP (requalified) — two-component system response regulator PhoP phoP phoR (requalified) — sensory box histidine kinase PhoR phoR Rv1125 (family_assigned) — WS/DGAT domain-containing protein Rv1125 lprB (family_assigned) — DUF3558 domain-containing protein lprB Rv3906c (requalified) — pullulanase Rv3906c ttfA (requalified) — trehalose monomycolate transport factor TtfA ttfA lprC (family_assigned) — DUF3558 domain-containing protein lprC Rv2342 (family_assigned) — hypothetical protein Rv2342 Rv2876 (requalified) — transmembrane protein Rv2876 pirG (requalified) — exported repetitive protein pirG Rv0466 (requalified) — acyl-[acyl-carrier-protein] thioesterase Rv0466 Rv0513 (family_assigned) — DUF3093 domain-containing protein Rv0513 Rv0600c (requalified) — two component sensor kinase HK1 Rv0600c prrB (requalified) — two-component system sensor histidine kinase PrrB prrB trcS (family_assigned) — HAMP domain-containing sensor histidine kinase trcS tcrY (requalified) — two component sensor kinase TcrY tcrY senX3 (requalified) — two-component system sensor histidine kinase SenX3 senX3 tcrX (requalified) — two-component system response regulator TcrX tcrX mtrA (requalified) — two-component system response regulator MtrA mtrA trcR (requalified) — two-component system response regulator TrcR trcR prrA (requalified) — two-component system response regulator PrrA prrA tcrA (family_assigned) — two component DNA binding transcriptional regulato tcrA ephC (requalified) — epoxide hydrolase EphC ephC pks13 (requalified) — polyketide synthase Pks13 pks13 pks12 (requalified) — type I polyketide synthase pks12 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 rplS (requalified) — 50S ribosomal protein L19 rplS rplT (requalified) — 50S ribosomal protein L20 rplT rplQ (requalified) — 50S ribosomal protein L17 rplQ rplM (requalified) — 50S ribosomal protein L13 rplM rplN (requalified) — 50S ribosomal protein L14 rplN pcnA (requalified) — poly(A) polymerase PcnA pcnA murJ (requalified) — murein biosynthesis integral membrane protein MurJ murJ Rv3909 (dark) — hypothetical protein Rv3909 Rv0385 (requalified) — FAD-binding oxidoreductase Rv0385 pyrE (requalified) — orotate phosphoribosyltransferase pyrE pyrD (requalified) — quinone-dependent dihydroorotate dehydrogenase pyrD carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB Rv0381c (dark) — hypothetical protein Rv0381c rpmA (requalified) — 50S ribosomal protein L27 rpmA rplU (requalified) — 50S ribosomal protein L21 rplU Rv3802c (requalified) — phospholipase Rv3802c aftC (requalified) — arabinofuranan 3-O-arabinosyltransferase aftC

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.