Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0746 · 45 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
PE_PGRS9 (family_assigned) — PE-PGRS family protein PE_PGRS9 PE_PGRS9 Rv0745 (family_assigned) — hypothetical protein Rv0745 Rv0743c (family_assigned) — DUF6036 family nucleotidyltransferase Rv0743c Rv0744c (family_assigned) — helix-turn-helix domain-containing protein Rv0744c zmp1 (requalified) — zinc metalloprotease Zmp1 zmp1 fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH lppB (family_assigned) — LppA family lipoprotein lppB lppA (family_assigned) — LppA family lipoprotein lppA aroG (requalified) — 3-deoxy-7-phosphoheptulonate synthase class II aroG PPE9 (family_assigned) — PPE family protein PPE9 PPE9 PE_PGRS37 (family_assigned) — PE-PGRS family protein PE_PGRS37 PE_PGRS37 Rv2891 (family_assigned) — hypothetical protein Rv2891 Rv0648 (requalified) — alpha-mannosidase Rv0648 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 galK (requalified) — galactokinase galK cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT Rv1682 (family_assigned) — hypothetical protein Rv1682 vapC31 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC31 vapC48 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC48 Rv1776c (family_assigned) — TetR/AcrR family transcriptional regulator Rv1776c Rv3167c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3167c cobB (requalified) — NAD-dependent protein deacylase cobB Rv3830c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3830c Rv0603 (family_assigned) — hypothetical protein Rv0603 omamA (requalified) — hypothetical protein omamA omamB (requalified) — hypothetical protein omamB polA (requalified) — DNA polymerase I polA ruvB (requalified) — Holliday junction branch migration DNA helicase Ru ruvB Rv3633 (family_assigned) — phytanoyl-CoA dioxygenase family protein Rv3633 Rv1501 (family_assigned) — phytanoyl-CoA dioxygenase family protein Rv1501 gltB (family_assigned) — glutamate synthase large subunit gltB fixA (family_assigned) — electron transfer flavoprotein subunit beta/FixA f fixA Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 fixB (family_assigned) — electron transfer flavoprotein subunit alpha/FixB fixB Rv1176c (family_assigned) — PadR family transcriptional regulator Rv1176c narH (family_assigned) — nitrate reductase subunit beta narH vapB18 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB18 Rv2542 (family_assigned) — alpha/beta hydrolase family protein Rv2542 vapC18 (family_assigned) — PIN domain nuclease vapC18 vapC19 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC19 vapB19 (family_assigned) — CopG family transcriptional regulator vapB19 Rv0948c (requalified) — chorismate mutase Rv0948c aroB (requalified) — 3-dehydroquinate synthase aroB Rv2179c (requalified) — polyadenylate-specific 3'-exoribonuclease AS Rv2179c

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.