MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0646c · 45 genes shown · anchor mmaA1 · open gene page → · ← back to 1 hop

Evidence: Min score 0
lipG (requalified) — lipase/esterase LipG lipG Rv0647c (family_assigned) — hypothetical protein Rv0647c mmaA1 (requalified) — mycolic acid methyltransferase MmaA1 mmaA1 Rv0648 (requalified) — alpha-mannosidase Rv0648 Rv0650 (family_assigned) — ROK family protein Rv0650 fabD2 (requalified) — malonyl CoA-acyl carrier protein transacylase fabD2 Rv0221 (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr Rv0221 mas (requalified) — mycocerosate synthase mas pks12 (requalified) — type I polyketide synthase pks12 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC tgs4 (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr tgs4 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mmaA2 (requalified) — cyclopropane mycolic acid synthase MmaA2 mmaA2 Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c Rv0745 (family_assigned) — hypothetical protein Rv0745 galK (requalified) — galactokinase galK Rv1999c (family_assigned) — APC family permease Rv1999c Rv0371c (family_assigned) — NTP transferase domain-containing protein Rv0371c pgi (requalified) — glucose-6-phosphate isomerase pgi pgmA (requalified) — phosphoglucomutase (alpha-D-glucose-1%2C6-bisphosp pgmA ino1 (requalified) — inositol-3-phosphate synthase ino1 ppgK (family_assigned) — ROK family protein ppgK accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 fas (requalified) — fatty acid synthase fas accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 fabG2 (requalified) — 3-oxoacyl-ACP reductase FabG fabG2 echA1 (family_assigned) — crotonase/enoyl-CoA hydratase family protein echA1 lipY (requalified) — triacylglycerol lipase Lip lipY Rv2252 (requalified) — diacylglycerol kinase Rv2252 lipC (requalified) — esterase LipC lipC Rv3233c (family_assigned) — Possible triacylglycerol synthase (diacylglycerol Rv3233c Rv0218 (requalified) — molybdopterin-dependent oxidoreductase Rv0218 fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD mbtB (requalified) — phenyloxazoline synthase MbtB mbtB ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB fadD13 (requalified) — long-chain-fatty-acid--CoA ligase FadD13 fadD13 Rv3087 (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr Rv3087 adhD (requalified) — NDMA-dependent alcohol dehydrogenase adhD Rv3083 (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv3083 Rv3085 (family_assigned) — SDR family NAD(P)-dependent oxidoreductase Rv3085 lipR (family_assigned) — alpha/beta hydrolase lipR papA1 (requalified) — acyltransferase PapA1 papA1

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.