MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0644c · 46 genes shown · anchor mmaA3 · open gene page → · ← back to 1 hop

Evidence: Min score 0
mmaA2 (requalified) — cyclopropane mycolic acid synthase MmaA2 mmaA2 rplY (requalified) — 50S ribosomal protein L25/general stress protein C rplY mmaA3 (requalified) — methoxy mycolic acid synthase MmaA3 mmaA3 mmaA4 (requalified) — hydroxymycolate synthase MmaA4 mmaA4 Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c mmaA1 (requalified) — mycolic acid methyltransferase MmaA1 mmaA1 lipG (requalified) — lipase/esterase LipG lipG Rv0647c (family_assigned) — hypothetical protein Rv0647c fabG1 (requalified) — 3-oxoacyl-ACP reductase FabG1 fabG1 ctpE (requalified) — cation-translocating P-type ATPase ctpE Rv3787c (requalified) — class I SAM-dependent methyltransferase Rv3787c rplI (requalified) — 50S ribosomal protein L9 rplI rpmD (requalified) — 50S ribosomal protein L30 rpmD rpsC (requalified) — 30S ribosomal protein S3 rpsC rplU (requalified) — 50S ribosomal protein L21 rplU rplQ (requalified) — 50S ribosomal protein L17 rplQ rplD (requalified) — 50S ribosomal protein L4 rplD Rv0448c (dark) — hypothetical protein Rv0448c hadB (family_assigned) — (3R)-hydroxyacyl-ACP dehydratase subunit HadB hadB pks13 (requalified) — polyketide synthase Pks13 pks13 pcaA (requalified) — cyclopropane mycolic acid synthase pcaA hadA (family_assigned) — (3R)-hydroxyacyl-ACP dehydratase subunit HadA hadA ufaA1 (requalified) — class I SAM-dependent methyltransferase ufaA1 Rv0446c (family_assigned) — DUF1295 domain-containing protein Rv0446c cmaA1 (requalified) — cyclopropane mycolic acid synthase CmaA1 cmaA1 sigK (family_assigned) — sigma-70 family RNA polymerase sigma factor SigK sigK mmpL4 (requalified) — transmembrane transport protein MmpL4 mmpL4 fabD2 (requalified) — malonyl CoA-acyl carrier protein transacylase fabD2 Rv0650 (family_assigned) — ROK family protein Rv0650 Rv0648 (requalified) — alpha-mannosidase Rv0648 Rv0221 (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr Rv0221 inhA (requalified) — NADH-dependent enoyl-ACP reductase InhA inhA hemZ (requalified) — ferrochelatase hemZ fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC fas (requalified) — fatty acid synthase fas kasB (requalified) — 3-oxoacyl-ACP synthase 2 kasB Rv0907 (family_assigned) — hypothetical protein Rv0907 Rv0906 (requalified) — MBL fold metallo-hydrolase Rv0906 echA6 (requalified) — enoyl-CoA hydratase echA6 Rv1747 (family_assigned) — ATP-binding cassette domain-containing protein Rv1747 atpE (family_assigned) — F0F1 ATP synthase subunit C atpE Rv0909 (requalified) — antitoxin Rv0909 Rv3786c (family_assigned) — peptidoglycan DD-metalloendopeptidase family prote Rv3786c Rv3788 (family_assigned) — GreA/GreB family elongation factor Rv3788 cmaA2 (requalified) — cyclopropane mycolic acid synthase CmaA2 cmaA2

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.