MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0642c · 46 genes shown · anchor mmaA3 · open gene page → · ← back to 1 hop

Evidence: Min score 0
mmaA4 (requalified) — hydroxymycolate synthase MmaA4 mmaA4 mmaA3 (requalified) — methoxy mycolic acid synthase MmaA3 mmaA3 Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c mmaA2 (requalified) — cyclopropane mycolic acid synthase MmaA2 mmaA2 pcaA (requalified) — cyclopropane mycolic acid synthase pcaA hadA (family_assigned) — (3R)-hydroxyacyl-ACP dehydratase subunit HadA hadA pks13 (requalified) — polyketide synthase Pks13 pks13 Rv0892 (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0892 Rv1729c (requalified) — class I SAM-dependent methyltransferase Rv1729c Rv0448c (dark) — hypothetical protein Rv0448c hadB (family_assigned) — (3R)-hydroxyacyl-ACP dehydratase subunit HadB hadB ufaA1 (requalified) — class I SAM-dependent methyltransferase ufaA1 Rv0446c (family_assigned) — DUF1295 domain-containing protein Rv0446c cmaA1 (requalified) — cyclopropane mycolic acid synthase CmaA1 cmaA1 sigK (family_assigned) — sigma-70 family RNA polymerase sigma factor SigK sigK mmpL4 (requalified) — transmembrane transport protein MmpL4 mmpL4 rplY (requalified) — 50S ribosomal protein L25/general stress protein C rplY mmaA1 (requalified) — mycolic acid methyltransferase MmaA1 mmaA1 lipG (requalified) — lipase/esterase LipG lipG lprG (requalified) — lipoarabinomannan carrier protein LprG lprG Rv0470A (family_assigned) — hypothetical protein Rv0470A Rv0471c (requalified) — 1%2C4-dihydroxy-2-naphthoate prenyltransferase Rv0471c Rv0472c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0472c Rv2954c (requalified) — [2%2C4-di-O-methyl-alpha-L-fucopyranosyl-(1->3)-al Rv2954c hadC (family_assigned) — (3R)-hydroxyacyl-ACP dehydratase subunit HadC hadC rpmG2 (requalified) — 50S ribosomal protein L33 rpmG2 rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA icd1 (requalified) — NADP-dependent isocitrate dehydrogenase icd1 echA3 (family_assigned) — crotonase/enoyl-CoA hydratase family protein echA3 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 Rv3741c (requalified) — oxidoreductase Rv3741c Rv3742c (requalified) — oxidoreductase Rv3742c atpA (family_assigned) — F0F1 ATP synthase subunit alpha atpA Rv1507c (family_assigned) — WbqC family protein Rv1507c lipY (requalified) — triacylglycerol lipase Lip lipY atpG (family_assigned) — F0F1 ATP synthase subunit gamma atpG Rv1728c (requalified) — glycoside hydrolase Rv1728c Rv1730c (family_assigned) — serine hydrolase domain-containing protein Rv1730c pptT (requalified) — 4'-phosphopantetheinyl transferase pptT eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 Rv3177 (family_assigned) — alpha/beta hydrolase Rv3177

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.