MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0625c · 46 genes shown · anchor vapB5 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0625c (family_assigned) — TVP38/TMEM64 family protein Rv0625c vapB5 (family_assigned) — type II toxin-antitoxin system Phd/YefM family ant vapB5 vapC5 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC5 Rv1978 (requalified) — class I SAM-dependent methyltransferase Rv1978 eccE1 (family_assigned) — type VII secretion system ESX-1 subunit EccE1 eccE1 eccD1 (family_assigned) — type VII secretion system ESX-1 subunit EccD1 eccD1 Rv2633c (requalified) — non-heme di-iron catalase Rv2633c esxA (requalified) — ESAT-6 protein EsxA esxA Rv2687c (family_assigned) — fluoroquinolone transporter permease Rv2687c moeY (family_assigned) — Rv1355c family protein moeY Rv2181 (requalified) — alpha-(1-2)-phosphatidylinositol mannoside mannosy Rv2181 Rv0204c (family_assigned) — TIGR00374 family protein Rv0204c Rv3483c (family_assigned) — LppP/LprE family lipoprotein Rv3483c vapC8 (family_assigned) — PIN domain-containing protein vapC8 vapC4 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC4 vapC47 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC47 vapC46 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC46 Rv3479 (requalified) — transmembrane protein Rv3479 vapB4 (requalified) — type II toxin-antitoxin system antitoxin VapB4 vapB4 Rv1871c (family_assigned) — nitroreductase family deazaflavin-dependent oxidor Rv1871c Rv2686c (family_assigned) — fluoroquinolones efflux ABC transporter permease Rv2686c rsmA (requalified) — anti-sigma-M factor RsmA rsmA Rv0210 (family_assigned) — hypothetical protein Rv0210 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 Rv3604c (dark) — DUF6779 domain-containing protein Rv3604c mycP1 (requalified) — type VII secretion system ESX-1 serine protease my mycP1 eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 espK (family_assigned) — ESX-1 secretion-associated protein EspK espK eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 espB (requalified) — type VII secretion system ESX-1 target EspB espB espI (family_assigned) — MinD/ParA family protein espI eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 Rv2632c (family_assigned) — DUF1876 domain-containing protein Rv2632c Rv3896c (requalified) — transglycosylase Rv3896c Rv0955 (family_assigned) — DUF6350 family protein Rv0955 Rv0688 (requalified) — FAD/NAD(P)-binding oxidoreductase Rv0688 Rv1869c (requalified) — FAD-dependent oxidoreductase Rv1869c esxB (family_assigned) — type VII secretion system ESX-1 WXG100 family targ esxB esxO (requalified) — type VII secretion system effector EsxO esxO esxW (requalified) — type VII secretion system protein EsxW esxW Rv2688c (family_assigned) — ABC transporter ATP-binding protein Rv2688c Rv1354c (requalified) — bifunctional diguanylate cyclase/phosphodiesterase Rv1354c Rv1356c (requalified) — hypothetical protein Rv1356c Rv1353c (family_assigned) — TetR/AcrR family transcriptional regulator C-termi Rv1353c Rv1358 (family_assigned) — LuxR C-terminal-related transcriptional regulator Rv1358 Rv1357c (requalified) — cyclic diguanylate phosphodiesterase Rv1357c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.