MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0574c · 46 genes shown · anchor pncB2 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0574c (family_assigned) — CapA family protein Rv0574c pncB2 (requalified) — nicotinate phosphoribosyltransferase pncB2 ctpF (requalified) — cation-transporting P-type ATPase ctpF Rv0571c (family_assigned) — phosphoribosyltransferase family protein Rv0571c Rv2030c (family_assigned) — erythromycin esterase family protein Rv2030c Rv2143 (family_assigned) — phosphoribosyltransferase family protein Rv2143 Rv0575c (requalified) — FAD-binding domain Rv0575c Rv2625c (family_assigned) — site-2 protease family protein Rv2625c Rv0579 (family_assigned) — Mut7-C RNAse domain-containing protein Rv0579 Rv2624c (requalified) — universal stress protein Rv2624c Rv1734c (family_assigned) — hypothetical protein Rv1734c pncA (requalified) — pyrazinamidase PncA pncA nadC (requalified) — carboxylating nicotinate-nucleotide diphosphorylas nadC pncB1 (requalified) — nicotinate phosphoribosyltransferase pncB1 cinA (requalified) — competence/damage-inducible protein A cinA nadR (requalified) — nicotinamide-nucleotide adenylyltransferase nadR pfkB (family_assigned) — 1-phosphofructokinase family hexose kinase pfkB Rv2028c (requalified) — universal stress protein Rv2028c narX (family_assigned) — respiratory nitrate reductase subunit gamma narX Rv2004c (family_assigned) — AAA family ATPase Rv2004c otsB1 (requalified) — trehalose-6-phosphate phosphatase OtsB otsB1 Rv2003c (family_assigned) — hypothetical protein Rv2003c Rv2630 (requalified) — archease Rv2630 nrdZ (requalified) — adenosylcobalamin-dependent ribonucleoside-diphosp nrdZ hspX (requalified) — alpha-crystallin HspX hspX acg (family_assigned) — FMN-binding protein Acg acg hrp1 (requalified) — hypoxic response protein Hrp1 hrp1 parE2 (family_assigned) — type II toxin-antitoxin system RelE/ParE family to parE2 parD2 (requalified) — antitoxin ParD2 parD2 dapA (requalified) — 4-hydroxy-tetrahydrodipicolinate synthase dapA Rv1405c (requalified) — virulence-associated methyltransferase Rv1405c Rv1403c (requalified) — class I SAM-dependent methyltransferase Rv1403c erg3 (requalified) — membrane-bound C-5 sterol desaturase erg3 Rv0576 (family_assigned) — TIGR03086 family metal-binding protein Rv0576 TB27.3 (family_assigned) — VOC family protein TB27.3 galK (requalified) — galactokinase galK Rv2631 (requalified) — RNA-splicing ligase RtcB Rv2631 vapB26 (requalified) — type II toxin-antitoxin system antitoxin VapB26 vapB26 vapC26 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC26 Rv2466c (family_assigned) — Rv2466c family mycothiol-dependent reductase Rv2466c bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c Rv0843 (family_assigned) — thiamine pyrophosphate-dependent dehydrogenase E1 Rv0843 bkdA (family_assigned) — pyruvate dehydrogenase (acetyl-transferring) E1 co bkdA sthA (requalified) — Si-specific NAD(P)(+) transhydrogenase sthA lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.