MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0568 · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
cyp135B1 (requalified) — cytochrome P450 cyp135B1 pks13 (requalified) — polyketide synthase Pks13 pks13 mbtE (requalified) — peptide synthetase mbtE Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 fdxB (requalified) — fatty acid desaturase fdxB rplF (requalified) — 50S ribosomal protein L6 rplF polA (requalified) — DNA polymerase I polA pks1 (requalified) — polyketide synthase pks1 ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mas (requalified) — mycocerosate synthase mas pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks12 (requalified) — type I polyketide synthase pks12 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 mbtC (requalified) — polyketide synthetase MbtC mbtC mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH fprB (requalified) — FAD-dependent oxidoreductase fprB fprA (requalified) — ferredoxin--NADP(+) reductase FprA fprA gltD (family_assigned) — glutamate synthase subunit beta gltD ephB (requalified) — epoxide hydrolase EphB ephB ribA1 (requalified) — riboflavin biosynthesis protein RibA ribA1 Rv1465 (family_assigned) — SUF system NifU family Fe-S cluster assembly prote Rv1465 iscS (family_assigned) — cysteine desulfurase family protein iscS rpsD (requalified) — 30S ribosomal protein S4 rpsD rplW (requalified) — 50S ribosomal protein L23 rplW rpsG (requalified) — 30S ribosomal protein S7 rpsG rplS (requalified) — 50S ribosomal protein L19 rplS rpsR1 (requalified) — 30S ribosomal protein S18 rpsR1 rplB (requalified) — 50S ribosomal protein L2 rplB dnaN (family_assigned) — DNA polymerase III subunit beta dnaN lppK (family_assigned) — hypothetical protein lppK recA (requalified) — intein-containing recombinase RecA recA Rv1277 (family_assigned) — hypothetical protein Rv1277 Rv2529 (family_assigned) — hypothetical protein Rv2529 Rv1278 (family_assigned) — AAA family ATPase Rv1278 pks15 (requalified) — polyketide synthase pks15 fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC ppsA (requalified) — phthiocerol type I polyketide synthase PpsA ppsA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.