MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0551c · 44 genes shown · anchor menC · open gene page → · ← back to 1 hop

Evidence: Min score 0
fadD8 (requalified) — fatty-acid--CoA ligase FadD8 fadD8 menC (requalified) — o-succinylbenzoate synthase menC Rv0552 (requalified) — amidohydrolase Rv0552 rplF (requalified) — 50S ribosomal protein L6 rplF pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 pks12 (requalified) — type I polyketide synthase pks12 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mas (requalified) — mycocerosate synthase mas ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks15 (requalified) — polyketide synthase pks15 bpoC (family_assigned) — alpha/beta hydrolase bpoC menB (requalified) — 1,4-dihydroxy-2-naphthoyl-CoA synthase menB pks13 (requalified) — polyketide synthase Pks13 pks13 menD (requalified) — 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1 menD menE (requalified) — o-succinylbenzoate--CoA ligase menE mgtA (requalified) — GDP-mannose-dependent alpha-mannosyltransferase mgtA Rv0556 (family_assigned) — DUF3592 domain-containing protein Rv0556 rpsD (requalified) — 30S ribosomal protein S4 rpsD rplW (requalified) — 50S ribosomal protein L23 rplW rpsG (requalified) — 30S ribosomal protein S7 rpsG rplS (requalified) — 50S ribosomal protein L19 rplS rpsR1 (requalified) — 30S ribosomal protein S18 rpsR1 rplB (requalified) — 50S ribosomal protein L2 rplB fas (requalified) — fatty acid synthase fas fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD mbtB (requalified) — phenyloxazoline synthase MbtB mbtB papA1 (requalified) — acyltransferase PapA1 papA1 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB pks1 (requalified) — polyketide synthase pks1 pks17 (requalified) — polyketide synthase pks17 fadD29 (requalified) — long-chain-fatty-acid--AMP ligase FadD29 fadD29 fadD22 (requalified) — p-hydroxybenzoic acid--AMP ligase FadD22 fadD22 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c hpx (requalified) — non-heme haloperoxidase Hpx hpx Rv1847 (family_assigned) — PaaI family thioesterase Rv1847 menA (requalified) — 1%2C4-dihydroxy-2-naphthoate polyprenyltransferase menA Rv0544c (family_assigned) — hypothetical protein Rv0544c mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.