MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0524 · 41 genes shown · anchor hemB · open gene page → · ← back to 1 hop

Evidence: Min score 0
hemL (requalified) — glutamate-1-semialdehyde 2%2C1-aminomutase hemL hemB (requalified) — porphobilinogen synthase hemB hemA (requalified) — glutamyl-tRNA reductase hemA Rv0525 (family_assigned) — histidine phosphatase family protein Rv0525 Rv0526 (requalified) — thioredoxin Rv0526 ccdA (requalified) — cytochrome C-type biogenesis protein CcdA ccdA hemC (requalified) — hydroxymethylbilane synthase hemC ccsA (requalified) — c-type cytochrome biogenesis protein CcsB ccsA Rv0528 (requalified) — cytochrome c biogenesis protein ResB Rv0528 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB rmlD (requalified) — dTDP-4-dehydrorhamnose reductase rmlD ask (requalified) — aspartate kinase ask hemD (requalified) — uroporphyrin-III C-methyltransferase hemD Rv0514 (dark) — hypothetical protein Rv0514 Rv0513 (family_assigned) — DUF3093 domain-containing protein Rv0513 gltS (requalified) — glutamate--tRNA ligase gltS Rv0508 (family_assigned) — glutaredoxin family protein Rv0508 Rv2699c (dark) — DUF4193 domain-containing protein Rv2699c ahpC (requalified) — peroxiredoxin AhpC ahpC cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG hemE (requalified) — uroporphyrinogen decarboxylase hemE Rv0260c (requalified) — uroporphyrinogen-III synthase Rv0260c mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtE (requalified) — peptide synthetase mbtE mbtC (requalified) — polyketide synthetase MbtC mbtC pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 rmlC (requalified) — dTDP-4-dehydrorhamnose 3%2C5-epimerase rmlC wbbL1 (requalified) — N-acetylglucosaminyl-diphospho-decaprenol L-rhamno wbbL1 rmlA (requalified) — glucose-1-phosphate thymidylyltransferase RfbA rmlA Rv3784 (requalified) — dTDP-glucose 4,6-dehydratase Rv3784 rmlB (requalified) — dTDP-glucose 4%2C6-dehydratase rmlB galE3 (requalified) — UDP-glucose 4-epimerase GalE galE3 asd (requalified) — aspartate-semialdehyde dehydrogenase asd thrA (requalified) — homoserine dehydrogenase thrA asnB (requalified) — asparagine synthase (glutamine-hydrolyzing) asnB purA (requalified) — adenylosuccinate synthase purA argG (requalified) — argininosuccinate synthase argG nadB (requalified) — L-aspartate oxidase nadB cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.