MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0512 · 36 genes shown · anchor hemC · open gene page → · ← back to 1 hop

Evidence: Min score 0
hemB (requalified) — porphobilinogen synthase hemB hemC (requalified) — hydroxymethylbilane synthase hemC hemL (requalified) — glutamate-1-semialdehyde 2%2C1-aminomutase hemL hemD (requalified) — uroporphyrin-III C-methyltransferase hemD Rv0514 (dark) — hypothetical protein Rv0514 hemA (requalified) — glutamyl-tRNA reductase hemA Rv0513 (family_assigned) — DUF3093 domain-containing protein Rv0513 cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG hemE (requalified) — uroporphyrinogen decarboxylase hemE Rv0508 (family_assigned) — glutaredoxin family protein Rv0508 Rv0260c (requalified) — uroporphyrinogen-III synthase Rv0260c cobM (requalified) — precorrin-4 C(11)-methyltransferase cobM Rv0526 (requalified) — thioredoxin Rv0526 Rv0525 (family_assigned) — histidine phosphatase family protein Rv0525 ccdA (requalified) — cytochrome C-type biogenesis protein CcdA ccdA cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ Rv0528 (requalified) — cytochrome c biogenesis protein ResB Rv0528 gltS (requalified) — glutamate--tRNA ligase gltS ubiA (requalified) — decaprenyl-phosphate phosphoribosyltransferase ubiA Rv0259c (family_assigned) — sirohydrochlorin chelatase Rv0259c cysC (requalified) — adenylyl-sulfate kinase cysC hemY (requalified) — protoporphyrinogen oxidase hemY hemZ (requalified) — ferrochelatase hemZ hemQ (requalified) — hydrogen peroxide-dependent heme synthase hemQ mmpS2 (family_assigned) — MmpS family protein mmpS2 mmpL2 (requalified) — RND transporter MmpL2 mmpL2 nrdE (family_assigned) — ribonucleoside-diphosphate reductase subunit alpha nrdE nrdZ (requalified) — adenosylcobalamin-dependent ribonucleoside-diphosp nrdZ narK3 (requalified) — nitrate/nitrite transporter narK3 cobL (requalified) — bifunctional cobalt-precorrin-7 (C(5))-methyltrans cobL cobK (requalified) — cobalt-precorrin-6A reductase cobK cobH (requalified) — precorrin-8X methylmutase cobH cobQ1 (requalified) — cobyric acid synthase cobQ1 cobB (requalified) — cobyrinate a%2Cc-diamide synthase cobB ccsA (requalified) — c-type cytochrome biogenesis protein CcsB ccsA ahpC (requalified) — peroxiredoxin AhpC ahpC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.