MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0511 · 37 genes shown · anchor hemC · open gene page → · ← back to 1 hop

Evidence: Min score 0
hemD (requalified) — uroporphyrin-III C-methyltransferase hemD hemC (requalified) — hydroxymethylbilane synthase hemC hemB (requalified) — porphobilinogen synthase hemB cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG hemA (requalified) — glutamyl-tRNA reductase hemA cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ Rv0514 (dark) — hypothetical protein Rv0514 Rv0513 (family_assigned) — DUF3093 domain-containing protein Rv0513 Rv0260c (requalified) — uroporphyrinogen-III synthase Rv0260c hemE (requalified) — uroporphyrinogen decarboxylase hemE ccsA (requalified) — c-type cytochrome biogenesis protein CcsB ccsA cysC (requalified) — adenylyl-sulfate kinase cysC Rv0528 (requalified) — cytochrome c biogenesis protein ResB Rv0528 hemL (requalified) — glutamate-1-semialdehyde 2%2C1-aminomutase hemL Rv0259c (family_assigned) — sirohydrochlorin chelatase Rv0259c gltS (requalified) — glutamate--tRNA ligase gltS Rv0508 (family_assigned) — glutaredoxin family protein Rv0508 cobM (requalified) — precorrin-4 C(11)-methyltransferase cobM cobH (requalified) — precorrin-8X methylmutase cobH cobK (requalified) — cobalt-precorrin-6A reductase cobK cobL (requalified) — bifunctional cobalt-precorrin-7 (C(5))-methyltrans cobL cobQ1 (requalified) — cobyric acid synthase cobQ1 cobG (requalified) — precorrin-3B synthase cobG ubiA (requalified) — decaprenyl-phosphate phosphoribosyltransferase ubiA narK3 (requalified) — nitrate/nitrite transporter narK3 hemY (requalified) — protoporphyrinogen oxidase hemY hemZ (requalified) — ferrochelatase hemZ hemQ (requalified) — hydrogen peroxide-dependent heme synthase hemQ Rv0526 (requalified) — thioredoxin Rv0526 ccdA (requalified) — cytochrome C-type biogenesis protein CcdA ccdA Rv0525 (family_assigned) — histidine phosphatase family protein Rv0525 subI (family_assigned) — sulfate ABC transporter substrate-binding protein subI cysD (family_assigned) — sulfate adenylyltransferase subunit CysD cysD cysT (family_assigned) — sulfate ABC transporter permease subunit CysT cysT cysH (requalified) — phosphoadenylyl-sulfate reductase cysH cysW (family_assigned) — sulfate ABC transporter permease subunit CysW cysW cysA1 (family_assigned) — sulfate ABC transporter ATP-binding protein CysA cysA1

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.