MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0505c · 46 genes shown · anchor cmaA2 · open gene page → · ← back to 1 hop

Evidence: Min score 0
serB1 (requalified) — phosphoserine phosphatase SerB serB1 Rv0508 (family_assigned) — glutaredoxin family protein Rv0508 Rv0504c (family_assigned) — MaoC family dehydratase N-terminal domain-containi Rv0504c cmaA2 (requalified) — cyclopropane mycolic acid synthase CmaA2 cmaA2 serC (requalified) — phosphoserine transaminase serC hisF (family_assigned) — imidazole glycerol phosphate synthase subunit HisF hisF glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 hemA (requalified) — glutamyl-tRNA reductase hemA hemC (requalified) — hydroxymethylbilane synthase hemC cysE (requalified) — serine O-acetyltransferase cysE hisH (family_assigned) — imidazole glycerol phosphate synthase subunit HisH hisH mmpL2 (requalified) — RND transporter MmpL2 mmpL2 mmpS2 (family_assigned) — MmpS family protein mmpS2 nrdE (family_assigned) — ribonucleoside-diphosphate reductase subunit alpha nrdE nrdZ (requalified) — adenosylcobalamin-dependent ribonucleoside-diphosp nrdZ hadB (family_assigned) — (3R)-hydroxyacyl-ACP dehydratase subunit HadB hadB icd1 (requalified) — NADP-dependent isocitrate dehydrogenase icd1 Rv2242 (family_assigned) — PucR family transcriptional regulator Rv2242 pepA (family_assigned) — S1C family serine protease pepA Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c pks13 (requalified) — polyketide synthase Pks13 pks13 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 fabG1 (requalified) — 3-oxoacyl-ACP reductase FabG1 fabG1 serA1 (requalified) — D-3-phosphoglycerate dehydrogenase serA1 serA2 (requalified) — D-3-phosphoglycerate dehydrogenase SerA serA2 thrC (requalified) — threonine synthase thrC serB2 (requalified) — phosphoserine phosphatase SerB serB2 Rv3684 (requalified) — lyase Rv3684 cysK1 (requalified) — O-acetylserine sulfhydrylase cysK1 hisA (requalified) — bifunctional 1-(5-phosphoribosyl)-5-((5-phosphorib hisA hisB (requalified) — imidazoleglycerol-phosphate dehydratase HisB hisB hisD (requalified) — histidinol dehydrogenase hisD hisI (requalified) — phosphoribosyl-AMP cyclohydrolase hisI hisC1 (requalified) — histidinol-phosphate aminotransferase hisC1 sdaA (requalified) — L-serine ammonia-lyase sdaA gcvB (requalified) — aminomethyl-transferring glycine dehydrogenase gcvB gcvT (requalified) — aminomethyltransferase gcvT purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD purN (requalified) — phosphoribosylglycinamide formyltransferase purN gcvH (requalified) — glycine cleavage system protein GcvH gcvH hemL (requalified) — glutamate-1-semialdehyde 2%2C1-aminomutase hemL hemD (requalified) — uroporphyrin-III C-methyltransferase hemD hemB (requalified) — porphobilinogen synthase hemB gltS (requalified) — glutamate--tRNA ligase gltS

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.