MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0470c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
pcaA (requalified) — cyclopropane mycolic acid synthase pcaA lprG (requalified) — lipoarabinomannan carrier protein LprG lprG Rv0470A (family_assigned) — hypothetical protein Rv0470A Rv0471c (requalified) — 1%2C4-dihydroxy-2-naphthoate prenyltransferase Rv0471c Rv0472c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0472c mmaA4 (requalified) — hydroxymycolate synthase MmaA4 mmaA4 Rv2954c (requalified) — [2%2C4-di-O-methyl-alpha-L-fucopyranosyl-(1->3)-al Rv2954c hbhA (requalified) — heparin-binding hemagglutinin HbhA hbhA pks13 (requalified) — polyketide synthase Pks13 pks13 kasB (requalified) — 3-oxoacyl-ACP synthase 2 kasB kasA (requalified) — 3-oxoacyl-ACP synthase KasA kasA fabH (requalified) — beta-ketoacyl-ACP synthase III fabH fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD Rv1410c (requalified) — aminoglycoside/tetracycline transporter Rv1410c ribC (requalified) — riboflavin synthase ribC eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 Rv2695 (requalified) — alpha/beta fold hydrolase Rv2695 Rv3415c (family_assigned) — hypothetical protein Rv3415c Rv2743c (family_assigned) — hypothetical protein Rv2743c PPE8 (family_assigned) — PPE family protein PPE8 PPE8 PE_PGRS28 (family_assigned) — PE-PGRS family protein PE_PGRS28 PE_PGRS28 PPE55 (family_assigned) — PPE family protein PPE55 PPE55 PPE56 (family_assigned) — PPE family protein PPE56 PPE56 Rv0473 (dark) — DUF445 domain-containing protein Rv0473 Rv0474 (family_assigned) — helix-turn-helix transcriptional regulator Rv0474 Rv1836c (family_assigned) — substrate-binding domain-containing protein Rv1836c Rv0476 (requalified) — transmembrane protein Rv0476 mmaA3 (requalified) — methoxy mycolic acid synthase MmaA3 mmaA3 Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c mmaA2 (requalified) — cyclopropane mycolic acid synthase MmaA2 mmaA2 hadA (family_assigned) — (3R)-hydroxyacyl-ACP dehydratase subunit HadA hadA iniB (requalified) — isoniazid-induced protein IniB iniB Rv2955c (requalified) — [2-O-methyl-alpha-L-fucopyranosyl-(1->3)-alpha-L-r Rv2955c Rv1004c (family_assigned) — hypothetical protein Rv1004c Rv2209 (requalified) — MFS transporter Rv2209 Rv0477 (dark) — DUF2599 domain-containing protein Rv0477 ttfA (requalified) — trehalose monomycolate transport factor TtfA ttfA Rv3850 (family_assigned) — DUF6474 family protein Rv3850 Rv0996 (family_assigned) — hypothetical protein Rv0996 Rv1109c (requalified) — lipid droplet-associated protein Rv1109c mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.