MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0462 · 33 genes shown · anchor dlaT · open gene page → · ← back to 1 hop

Evidence: Min score 0
lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c dlaT (requalified) — 2-oxoglutarate dehydrogenase%2C E2 component%2C di dlaT bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB bkdC (family_assigned) — dihydrolipoamide acetyltransferase family protein bkdC bkdA (family_assigned) — pyruvate dehydrogenase (acetyl-transferring) E1 co bkdA gcvH (requalified) — glycine cleavage system protein GcvH gcvH gcvT (requalified) — aminomethyltransferase gcvT aceE (requalified) — pyruvate dehydrogenase E1 component aceE gcvB (requalified) — aminomethyl-transferring glycine dehydrogenase gcvB glyA1 (requalified) — serine hydroxymethyltransferase glyA1 glyA2 (requalified) — serine hydroxymethyltransferase glyA2 Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c Rv0794c (requalified) — oxidoreductase Rv0794c garA (requalified) — glycogen accumulation regulator GarA garA sthA (requalified) — Si-specific NAD(P)(+) transhydrogenase sthA mtr (requalified) — mycothione reductase mtr lpdA (requalified) — NAD(P)H-quinone dehydrogenase lpdA sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC Rv0843 (family_assigned) — thiamine pyrophosphate-dependent dehydrogenase E1 Rv0843 accA1 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA1 mez (requalified) — NAD-dependent malic enzyme mez folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD pykA (requalified) — pyruvate kinase pykA purD (requalified) — phosphoribosylamine--glycine ligase purD purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH purN (requalified) — phosphoribosylglycinamide formyltransferase purN sdaA (requalified) — L-serine ammonia-lyase sdaA Rv2454c (family_assigned) — 2-oxoacid:ferredoxin oxidoreductase subunit beta Rv2454c icd2 (requalified) — NADP-dependent isocitrate dehydrogenase icd2 aroF (requalified) — chorismate synthase aroF pta (requalified) — phosphate acetyltransferase pta sucD (family_assigned) — succinyl-CoA ligase subunit alpha sucD

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.