MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0451c · 46 genes shown · anchor mmpL4 · open gene page → · ← back to 1 hop

Evidence: Min score 0
mmpS4 (requalified) — siderophore RND transporter accessory protein MmpS mmpS4 mmpL4 (requalified) — transmembrane transport protein MmpL4 mmpL4 Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c ufaA1 (requalified) — class I SAM-dependent methyltransferase ufaA1 Rv0446c (family_assigned) — DUF1295 domain-containing protein Rv0446c Rv0448c (dark) — hypothetical protein Rv0448c Rv0452 (family_assigned) — TetR family transcriptional regulator Rv0452 sigK (family_assigned) — sigma-70 family RNA polymerase sigma factor SigK sigK mmpL5 (requalified) — siderophore RND transporter MmpL5 mmpL5 Rv1501 (family_assigned) — phytanoyl-CoA dioxygenase family protein Rv1501 mhuD (requalified) — mycobilin-forming heme oxygenase MhuD mhuD PPE62 (family_assigned) — PPE family protein PPE62 PPE62 irtA (family_assigned) — iron ABC transporter ATP-binding protein/permease irtA Rv1598c (family_assigned) — nitroreductase family deazaflavin-dependent oxidor Rv1598c eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 Rv1303 (family_assigned) — ATP synthase subunit I Rv1303 lppX (requalified) — LppX_LprAFG lipoprotein lppX cmaA1 (requalified) — cyclopropane mycolic acid synthase CmaA1 cmaA1 Rv3840 (family_assigned) — transcriptional regulator Rv3840 Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 rskA (requalified) — anti-sigma-K factor RskA rskA mpt70 (family_assigned) — fasciclin domain-containing protein mpt70 Rv1556 (family_assigned) — TetR/AcrR family transcriptional regulator Rv1556 Rv2912c (family_assigned) — TetR/AcrR family transcriptional regulator Rv2912c mce3R (family_assigned) — TetR family transcriptional regulator Mce3R mce3R Rv1167c (family_assigned) — TetR/AcrR family transcriptional regulator Rv1167c Rv3830c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3830c Rv3167c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3167c sigM (requalified) — ECF RNA polymerase sigma factor SigM sigM mmpS5 (requalified) — siderophore transporter accessory protein MmpS5 mmpS5 mmpR5 (family_assigned) — siderophore transport transcriptional regulator Mm mmpR5 Rv3160c (family_assigned) — helix-turn-helix domain-containing protein Rv3160c Rv1500 (family_assigned) — glycosyltransferase family 2 protein Rv1500 Rv1502 (family_assigned) — hypothetical protein Rv1502 Rv1499 (requalified) — glycosyltransferase (part1) Rv1499 Rv1867 (requalified) — acetyl-CoA acetyltransferase Rv1867 Rv3351c (family_assigned) — hypothetical protein Rv3351c dprE1 (requalified) — decaprenylphospho-beta-D-ribofuranose 2-dehydrogen dprE1 lpqF (requalified) — serine hydrolase lpqF Rv3591c (family_assigned) — alpha/beta hydrolase Rv3591c hycE (family_assigned) — NADH-quinone oxidoreductase subunit C hycE Rv3594 (requalified) — N-acetylmuramoyl-L-alanine amidase Rv3594 Rv0959 (family_assigned) — VWA domain-containing protein Rv0959 PE_PGRS58 (family_assigned) — PE-PGRS family protein PE_PGRS58 PE_PGRS58 PPE5 (family_assigned) — PPE family protein PPE5 PPE5 PPE21 (family_assigned) — PPE family protein PPE21 PPE21

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.