MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0449c · 41 genes shown · anchor ufaA1 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c ufaA1 (requalified) — class I SAM-dependent methyltransferase ufaA1 Rv0446c (family_assigned) — DUF1295 domain-containing protein Rv0446c Rv0448c (dark) — hypothetical protein Rv0448c cmaA1 (requalified) — cyclopropane mycolic acid synthase CmaA1 cmaA1 sigK (family_assigned) — sigma-70 family RNA polymerase sigma factor SigK sigK mmpL4 (requalified) — transmembrane transport protein MmpL4 mmpL4 mmpS4 (requalified) — siderophore RND transporter accessory protein MmpS mmpS4 mmaA4 (requalified) — hydroxymycolate synthase MmaA4 mmaA4 mmaA1 (requalified) — mycolic acid methyltransferase MmaA1 mmaA1 rskA (requalified) — anti-sigma-K factor RskA rskA mmaA2 (requalified) — cyclopropane mycolic acid synthase MmaA2 mmaA2 Rv0452 (family_assigned) — TetR family transcriptional regulator Rv0452 Rv3840 (family_assigned) — transcriptional regulator Rv3840 Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 mpt70 (family_assigned) — fasciclin domain-containing protein mpt70 iunH (requalified) — nucleoside hydrolase IunH iunH pks13 (requalified) — polyketide synthase Pks13 pks13 Rv2172c (requalified) — mycobacterial-type methylenetetrahydrofolate reduc Rv2172c Rv3254 (requalified) — oxidoreductase Rv3254 sigM (requalified) — ECF RNA polymerase sigma factor SigM sigM Rv1598c (family_assigned) — nitroreductase family deazaflavin-dependent oxidor Rv1598c eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 Rv1303 (family_assigned) — ATP synthase subunit I Rv1303 lppX (requalified) — LppX_LprAFG lipoprotein lppX mmaA3 (requalified) — methoxy mycolic acid synthase MmaA3 mmaA3 pcaA (requalified) — cyclopropane mycolic acid synthase pcaA hadA (family_assigned) — (3R)-hydroxyacyl-ACP dehydratase subunit HadA hadA lipG (requalified) — lipase/esterase LipG lipG Rv0647c (family_assigned) — hypothetical protein Rv0647c fabD2 (requalified) — malonyl CoA-acyl carrier protein transacylase fabD2 Rv0650 (family_assigned) — ROK family protein Rv0650 Rv2164c (family_assigned) — hypothetical protein Rv2164c ptrp (family_assigned) — hypothetical protein ptrp rplY (requalified) — 50S ribosomal protein L25/general stress protein C rplY Rv1556 (family_assigned) — TetR/AcrR family transcriptional regulator Rv1556 Rv2912c (family_assigned) — TetR/AcrR family transcriptional regulator Rv2912c mce3R (family_assigned) — TetR family transcriptional regulator Mce3R mce3R Rv1167c (family_assigned) — TetR/AcrR family transcriptional regulator Rv1167c Rv3830c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3830c Rv3167c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3167c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.