MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0445c · 46 genes shown · anchor rskA · open gene page → · ← back to 1 hop

Evidence: Min score 0
sigK (family_assigned) — sigma-70 family RNA polymerase sigma factor SigK sigK rskA (requalified) — anti-sigma-K factor RskA rskA Rv0448c (dark) — hypothetical protein Rv0448c Rv0446c (family_assigned) — DUF1295 domain-containing protein Rv0446c ufaA1 (requalified) — class I SAM-dependent methyltransferase ufaA1 Rv0449c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv0449c sigM (requalified) — ECF RNA polymerase sigma factor SigM sigM mpt83 (requalified) — cell surface glycolipoprotein Mpt83 mpt83 mpt70 (family_assigned) — fasciclin domain-containing protein mpt70 rslA (requalified) — anti-sigma-L factor RslA rslA rshA (requalified) — anti-sigma factor RshA rshA rseA (requalified) — anti-sigma E factor RseA rseA rpoC (family_assigned) — DNA-directed RNA polymerase subunit beta' rpoC Rv2164c (family_assigned) — hypothetical protein Rv2164c ptrp (family_assigned) — hypothetical protein ptrp mmpL4 (requalified) — transmembrane transport protein MmpL4 mmpL4 Rv3840 (family_assigned) — transcriptional regulator Rv3840 Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 cmaA1 (requalified) — cyclopropane mycolic acid synthase CmaA1 cmaA1 rsmA (requalified) — anti-sigma-M factor RsmA rsmA Rv3909 (dark) — hypothetical protein Rv3909 murJ (requalified) — murein biosynthesis integral membrane protein MurJ murJ mutT4 (requalified) — NUDIX hydrolase mutT4 sigC (requalified) — RNA polymerase sigma factor SigC sigC trxB2 (requalified) — thioredoxin-disulfide reductase trxB2 nuoD (family_assigned) — NADH dehydrogenase (quinone) subunit D nuoD dxr (requalified) — 1-deoxy-D-xylulose-5-phosphate reductoisomerase dxr rip (requalified) — zinc metalloprotease Rip rip dipZ (requalified) — integral membrane C-type cytochrome biogenesis pro dipZ vapC43 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC43 vapB43 (family_assigned) — ribbon-helix-helix domain-containing protein vapB43 Rv2876 (requalified) — transmembrane protein Rv2876 nuoI (family_assigned) — NADH-quinone oxidoreductase subunit NuoI nuoI sigL (family_assigned) — sigma-70 family RNA polymerase sigma factor SigL sigL Rv1145 (requalified) — transmembrane transport protein Rv1145 Rv0737 (family_assigned) — MarR family transcriptional regulator Rv0737 Rv1138c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv1138c pks10 (requalified) — type III polyketide synthase pks10 Rv1146 (requalified) — transmembrane transport protein Rv1146 sigH (family_assigned) — sigma-70 family RNA polymerase sigma factor SigH sigH Rv3222c (family_assigned) — hypothetical protein Rv3222c TB7.3 (requalified) — biotin/lipoyl-binding carrier protein TB7.3 Rv3224 (requalified) — NAD(P)-dependent oxidoreductase Rv3224 Rv3224B (family_assigned) — Conserved hypothetical protein Rv3224B moeB1 (requalified) — adenylyltransferase/sulfurtransferase MoeZ moeB1 tatB (requalified) — Sec-independent protein translocase protein TatB tatB

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.