Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv0421c · 46 genes shown · anchor thiD · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv0421c (family_assigned) — alpha/beta family hydrolase Rv0421c thiD (requalified) — hydroxymethylpyrimidine/phosphomethylpyrimidine ki thiD thiC (requalified) — phosphomethylpyrimidine synthase ThiC thiC Rv3693 (family_assigned) — DUF58 domain-containing protein Rv3693 Rv0420c (requalified) — transmembrane protein Rv0420c Rv0424c (dark) — hypothetical protein Rv0424c Rv2828A (dark) — hypothetical protein Rv2828A Rv2923c (family_assigned) — OsmC family protein Rv2923c Rv1841c (family_assigned) — hemolysin family protein Rv1841c cut5b (family_assigned) — Probable cutinase [second part] Cut5b cut5b mprB (requalified) — two-component system sensor histidine kinase MprB mprB ruvA (requalified) — Holliday junction branch migration protein RuvA ruvA hemQ (requalified) — hydrogen peroxide-dependent heme synthase hemQ thiE (requalified) — thiamine phosphate synthase thiE thiG (requalified) — thiazole synthase thiG thiS (requalified) — sulfur carrier protein ThiS thiS rhlE (requalified) — DEAD/DEAH box helicase rhlE fbiC (requalified) — bifunctional FO biosynthesis protein CofGH fbiC Rv3691 (family_assigned) — hypothetical protein Rv3691 Rv3690 (family_assigned) — DUF4129 domain-containing protein Rv3690 moxR2 (family_assigned) — MoxR family ATPase moxR2 Rv3689 (requalified) — transmembrane protein Rv3689 Rv3694c (requalified) — stage II sporulation protein M Rv3694c Rv3695 (family_assigned) — RDD family protein Rv3695 Rv0426c (dark) — hypothetical protein Rv0426c ctpH (requalified) — cation-translocating P-type ATPase ctpH xthA (requalified) — exodeoxyribonuclease III protein XthA xthA Rv2828c (family_assigned) — DUF1802 family protein Rv2828c vapB22 (family_assigned) — type II toxin-antitoxin system prevent-host-death vapB22 vapC22 (family_assigned) — PIN domain-containing protein vapC22 echA16 (requalified) — enoyl-CoA hydratase echA16 ligC (requalified) — ATP-dependent DNA ligase ligC Rv1156 (requalified) — HhH-GPD-type base excision DNA repair protein Rv1156 acyP (requalified) — acylphosphatase acyP smc (requalified) — chromosome segregation protein SMC smc ftsY (requalified) — signal recognition particle-docking protein FtsY ftsY fpg (requalified) — DNA-formamidopyrimidine glycosylase fpg sepIVA (requalified) — cell division protein SepIVA sepIVA rnc (requalified) — ribonuclease III rnc Rv1842c (family_assigned) — hemolysin family protein Rv1842c guaB1 (family_assigned) — GuaB1 family IMP dehydrogenase-related protein guaB1 gnd1 (requalified) — 6-phosphogluconate dehydrogenase gnd1 blaR (family_assigned) — M56 family metallopeptidase blaR blaI (requalified) — transcriptional repressor BlaI blaI glcB (requalified) — malate synthase G glcB cut5a (family_assigned) — Probable cutinase precursor [first part] Cut5a cut5a

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.